eF-site ID 6nee-AB PDB Code 6nee Chain A, B click to enlarge Title Crystal structure of a reconstructed ancestor of Triosephosphate isomerase from eukaryotes Classification ISOMERASE Compound TRIOSEPHOSPHATE ISOMERASE Source (6NEE) Sequence A:  SRKFFVGGNWKMNGTLESIKALVETLNSAQLDPNTEVVVA PPAIYLPFARSKLKKPKEIQVAAQNCYTKPNGAFTGEISA EMLKDLGVPWVILGHSERRTIFGESDELIAEKVKYALDQG LKVIACIGETLEEREAGKTMEVVARQILKAIADKIKDWSN VVIAYEPVWAIGTGKVATPEQAQEVHAALRKWLKENVSPE VAESTRIIYGGSVNAANCKELAKQPDIDGFLVGGASLKAP EFVDIINARQ B:  MASRKFFVGGNWKMNGTLESIKALVETLNSAQLDPNTEVV VAPPAIYLPFARSKLKKPKEIQVAAQNCYTKPNGAFTGEI SAEMLKDLGVPWVILGHSERRTIFGESDELIAEKVKYALD QGLKVIACIGETLEEREAGKTMEVVARQILKAIADKIKDW SNVVIAYEPVWAIGTGKVATPEQAQEVHAALRKWLKENVS PEVAESTRIIYGGSVNAANCKELAKQPDIDGFLVGGASLK APEFVDIINARQ Description Functional site 1) chain A residue 10 type sequence N description binding site for residue PGH A 301 source : AC1 2) chain A residue 12 type sequence K description binding site for residue PGH A 301 source : AC1 3) chain A residue 96 type sequence H description binding site for residue PGH A 301 source : AC1 4) chain A residue 167 type sequence E description binding site for residue PGH A 301 source : AC1 5) chain A residue 171 type sequence A description binding site for residue PGH A 301 source : AC1 6) chain A residue 172 type sequence I description binding site for residue PGH A 301 source : AC1 7) chain A residue 173 type sequence G description binding site for residue PGH A 301 source : AC1 8) chain A residue 212 type sequence G description binding site for residue PGH A 301 source : AC1 9) chain A residue 213 type sequence S description binding site for residue PGH A 301 source : AC1 10) chain A residue 232 type sequence L description binding site for residue PGH A 301 source : AC1 11) chain A residue 234 type sequence G description binding site for residue PGH A 301 source : AC1 12) chain A residue 235 type sequence G description binding site for residue PGH A 301 source : AC1 13) chain B residue 10 type sequence N description binding site for residue PGH B 301 source : AC2 14) chain B residue 12 type sequence K description binding site for residue PGH B 301 source : AC2 15) chain B residue 96 type sequence H description binding site for residue PGH B 301 source : AC2 16) chain B residue 167 type sequence E description binding site for residue PGH B 301 source : AC2 17) chain B residue 171 type sequence A description binding site for residue PGH B 301 source : AC2 18) chain B residue 172 type sequence I description binding site for residue PGH B 301 source : AC2 19) chain B residue 173 type sequence G description binding site for residue PGH B 301 source : AC2 20) chain B residue 212 type sequence G description binding site for residue PGH B 301 source : AC2 21) chain B residue 213 type sequence S description binding site for residue PGH B 301 source : AC2 22) chain B residue 232 type sequence L description binding site for residue PGH B 301 source : AC2 23) chain B residue 234 type sequence G description binding site for residue PGH B 301 source : AC2 24) chain B residue 235 type sequence G description binding site for residue PGH B 301 source : AC2 25) chain A residue 165-175 type prosite sequence AYEPVWAIGTG description TIM_1 Triosephosphate isomerase active site. AYEPVWAIGTG source prosite : PS00171

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