|
|
eF-site ID
|
6ncp-B |
|
PDB Code
|
6ncp |
|
Chain
|
B |
|
click to enlarge
|
|
|
Title
|
Crystal structure of HIV-1 broadly neutralizing antibody ACS202 |
|
Classification
|
IMMUNE SYSTEM |
|
Compound
|
ACS202 Fab heavy chain |
|
Source
|
(6NCP) |
|
|
Sequence
|
B: |
AIRMTQSPSSLSASVGDRVTITCQASQDIKKSLNWYRQKP
GKAPELLIHDASILQTGVPSAFTASGSGTHFSFVINKLQP
EDVGTYFCQEYENLQFTFGPGTKVEIKRTVAAPSVFIFPP
SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ
ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQG
LSSPVTKSFNRG
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
3 |
| type |
|
| sequence |
R
|
| description |
binding site for residue GLY B 301
|
| source |
: AC2
|
|
|
2)
|
chain |
B |
| residue |
24 |
| type |
|
| sequence |
Q
|
| description |
binding site for residue GLY B 301
|
| source |
: AC2
|
|
|
3)
|
chain |
B |
| residue |
26 |
| type |
|
| sequence |
S
|
| description |
binding site for residue GLY B 301
|
| source |
: AC2
|
|
|
4)
|
chain |
B |
| residue |
192-198 |
| type |
prosite |
| sequence |
YACEVTH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH
|
| source |
prosite : PS00290
|
|
|
|