eF-site ID 6nc8-A PDB Code 6nc8 Chain A click to enlarge Title Lipid II flippase MurJ, inward occluded conformation Classification TRANSPORT PROTEIN Compound Lipid II flippase MurJ Source (MURJ_THEAB) Sequence A:  SILFSSILFSIATFFSRILGLFRDVLFAKYFGVSYELDAY FIAIMFPFFLRKVFGEGAMSSAFVPLYSEKSGEEKDKFLS SVINGFSLIILALVILSYFFPELIINLFGAGSSHETKILA KKLLLITSPSIYFIFLWAISYSILNTNNKFFWPALTPSIS NITIIIGTFLSTKYGIISPTIGFLIGSILMFFSIIKSIIK HKYYFTIKHFPHFLKLFFPTFMTMVVSQINTVVDMNVVSF YDKGSISYLQYASRFYLLPYGLFAVSVSTVVLSKISNDRK NFNYHLNDALKTTLFFTIPSMVGLIFLSTPIIRFFYEHGA FTSKDTLITSKILIAYTLGLPFYGIYSTISRSYHAIKNTK TPFIAATIVSLSNIILDIIFGLKYGPIGVALATSIAGIIG VLYLLFSVKTFPIKDFLKISLNSLIMLFVIYLTDFTDNEF WFLIQILIGILVYLIFSSIFYRDLIRR Description Functional site 1) chain A residue 235 type sequence D description binding site for residue NA A 501 source : AC1 2) chain A residue 374 type sequence N description binding site for residue NA A 501 source : AC1 3) chain A residue 378 type sequence D description binding site for residue NA A 501 source : AC1 4) chain A residue 390 type sequence V description binding site for residue NA A 501 source : AC1 5) chain A residue 394 type sequence T description binding site for residue NA A 501 source : AC1 6) chain A residue 175 type sequence Y description binding site for residue OLC A 502 source : AC2 7) chain A residue 179 type sequence S description binding site for residue OLC A 502 source : AC2 8) chain A residue 182 type sequence I description binding site for residue OLC A 502 source : AC2 9) chain A residue 23 type sequence F description binding site for residue OLC A 503 source : AC3 10) chain A residue 315 type sequence F description binding site for residue OLC A 503 source : AC3 11) chain A residue 319 type sequence H description binding site for residue OLC A 503 source : AC3 12) chain A residue 440 type sequence E description binding site for residue OLC A 503 source : AC3 13) chain A residue 369 type sequence I description binding site for residue OLC A 504 source : AC4 14) chain A residue 404 type sequence Y description binding site for residue OLC A 504 source : AC4 15) chain A residue 439 type sequence N description binding site for residue OLC A 504 source : AC4 16) chain A residue 441 type sequence F description binding site for residue OLC A 504 source : AC4 17) chain A residue 444 type sequence L description binding site for residue OLC A 504 source : AC4 18) chain A residue 407 type sequence F description binding site for residue OLC A 505 source : AC5 19) chain A residue 410 type sequence K description binding site for residue OLC A 505 source : AC5 20) chain A residue 441 type sequence F description binding site for residue OLC A 505 source : AC5 21) chain A residue 85 type sequence N description binding site for residue OLC A 506 source : AC6 22) chain A residue 89 type sequence L description binding site for residue OLC A 506 source : AC6 23) chain A residue 206 type sequence F description binding site for residue OLC A 506 source : AC6 24) chain A residue 207 type sequence T description binding site for residue OLC A 506 source : AC6 25) chain A residue 208 type sequence I description binding site for residue OLC A 506 source : AC6 26) chain A residue 189 type sequence I description binding site for residue OLC A 507 source : AC7 27) chain A residue 27 type sequence L description binding site for residue 1PE A 508 source : AC8 28) chain A residue 30 type sequence K description binding site for residue 1PE A 508 source : AC8 29) chain A residue 31 type sequence Y description binding site for residue 1PE A 508 source : AC8 30) chain A residue 319 type sequence H description binding site for residue 1PE A 508 source : AC8 31) chain A residue 283 type sequence F description binding site for residue 1PE A 509 source : AC9 32) chain A residue 284 type sequence N description binding site for residue 1PE A 509 source : AC9 33) chain A residue 408 type sequence S description binding site for residue 1PE A 509 source : AC9 34) chain A residue 409 type sequence V description binding site for residue 1PE A 509 source : AC9 35) chain A residue 285 type sequence Y description binding site for residue 1PE A 510 source : AD1 36) chain A residue 288 type sequence N description binding site for residue 1PE A 510 source : AD1 37) chain A residue 289 type sequence D description binding site for residue 1PE A 510 source : AD1 38) chain A residue 292 type sequence K description binding site for residue 1PE A 510 source : AD1 39) chain A residue 416 type sequence D description binding site for residue 1PE A 510 source : AD1 40) chain A residue 57-78 type TOPO_DOM sequence EGAMSSAFVPLYSEKSGEEKDK description Cytoplasmic => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI1 41) chain A residue 145-150 type TOPO_DOM sequence LNTNNK description Cytoplasmic => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI1 42) chain A residue 197-213 type TOPO_DOM sequence KSIIKHKYYFTIKHFPH description Cytoplasmic => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI1 43) chain A residue 272-287 type TOPO_DOM sequence VLSKISNDRKNFNYHL description Cytoplasmic => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI1 44) chain A residue 354-362 type TOPO_DOM sequence YHAIKNTKT description Cytoplasmic => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI1 45) chain A residue 408-416 type TOPO_DOM sequence SVKTFPIKD description Cytoplasmic => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI1 46) chain A residue 3-23 type TRANSMEM sequence ILFSSILFSIATFFSRILGLF description Helical => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI2 47) chain A residue 333-353 type TRANSMEM sequence ILIAYTLGLPFYGIYSTISRS description Helical => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI2 48) chain A residue 363-383 type TRANSMEM sequence PFIAATIVSLSNIILDIIFGL description Helical => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI2 49) chain A residue 387-407 type TRANSMEM sequence PIGVALATSIAGIIGVLYLLF description Helical => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI2 50) chain A residue 417-437 type TRANSMEM sequence FLKISLNSLIMLFVIYLTDFT description Helical => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI2 51) chain A residue 441-461 type TRANSMEM sequence FWFLIQILIGILVYLIFSSIF description Helical => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI2 52) chain A residue 36-56 type TRANSMEM sequence YELDAYFIAIMFPFFLRKVFG description Helical => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI2 53) chain A residue 79-99 type TRANSMEM sequence FLSSVINGFSLIILALVILSY description Helical => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI2 54) chain A residue 124-144 type TRANSMEM sequence LLLITSPSIYFIFLWAISYSI description Helical => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI2 55) chain A residue 151-171 type TRANSMEM sequence FFWPALTPSISNITIIIGTFL description Helical => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI2 56) chain A residue 176-196 type TRANSMEM sequence GIISPTIGFLIGSILMFFSII description Helical => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI2 57) chain A residue 214-238 type TRANSMEM sequence FLKLFFPTFMTMVVSQINTVVDMNV description Helical => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI2 58) chain A residue 250-271 type TRANSMEM sequence LQYASRFYLLPYGLFAVSVSTV description Helical => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI2 59) chain A residue 288-308 type TRANSMEM sequence NDALKTTLFFTIPSMVGLIFL description Helical => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI2 60) chain A residue 24-35 type TOPO_DOM sequence RDVLFAKYFGVS description Periplasmic => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI3 61) chain A residue 100-123 type TOPO_DOM sequence FFPELIINLFGAGSSHETKILAKK description Periplasmic => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI3 62) chain A residue 172-175 type TOPO_DOM sequence STKY description Periplasmic => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI3 63) chain A residue 239-249 type TOPO_DOM sequence VSFYDKGSISY description Periplasmic => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI3 64) chain A residue 309-332 type TOPO_DOM sequence STPIIRFFYEHGAFTSKDTLITSK description Periplasmic => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI3 65) chain A residue 384-386 type TOPO_DOM sequence KYG description Periplasmic => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI3 66) chain A residue 438-440 type TOPO_DOM sequence DNE description Periplasmic => ECO:0000269|PubMed:28024149 source Swiss-Prot : SWS_FT_FI3

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