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eF-site ID
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6n88-ABC |
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PDB Code
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6n88 |
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Chain
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A, B, C |
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click to enlarge
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Title
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Cryo-EM structure of the Importin7:Importin beta:Histone H1.0 complex |
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Classification
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TRANSPORT PROTEIN |
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Compound
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MGC52556 protein |
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Source
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(H10_HUMAN) |
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Sequence
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A: |
KEYNDFAEVFLKAFAVGVQQVLLKVLYQYKEKQYIAPRVL
QQTLNYFNQGVSHAVTWKNLKPHIQGIIQDVIFPLMCYTD
SDEDLWQEDVFEDFISPTTAAQTLLFTSCSKRKEVLQKTM
GFCYQILTEPAADPRKKDGALHMIGSLAEILLKKKIYKDQ
MEFMLQNHVFPLFSSELGYMRARACWVLHYFCEVKFKVDQ
NLQTALELTRRCLIDDREMPVKVEAAIALQVLISNQEKAK
EYIVPFIRPVMQALLHIIRETENDDLTNVIQKMICEYSEE
VTPIAVEMTQHLAMTFNQVIQTGPDEEGSDDKAVTAMGIL
NTIDTLLSVVEDHKEITQQLEGICLQVIGTVLQQHVLEFY
EEIFSLAHSLTCQQVSPQMWQLLPLVFDIFQQDGFDYFTD
MMPLLHNYVTVDTDTLLSDTKYLEMIYSMCKKILTGVAGE
DAECHAAKLLEVVILQCKGRGIDQVIPLFVEAALERLTRE
VKTSELRTMCLQVAIAALYYSPPLLFNTLENLRFPNNEEP
VTNHFIKQWLNDVDCFLGLHDRKICVLGLCALIELEQRPQ
VLNQMSSQILPAFLLLFNEYQIFKAIFQKLQGRDPVWYQA
LTQGLNEDQGKQLQDIATL
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| B: |
MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVEL
SRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRW
LAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAE
IPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQD
IDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLN
SLEFTKANFDKESERHFIMQVVCEATQCPDTRVRVAALQN
LVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGI
EFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKGALQ
YLVPILTQTLTKQDENDDDDDWNPCKAAGVCLMLLATCCE
DDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPS
QLKPLVIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLP
EAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAEA
AYEAADVADDQEEPATYCLSSSFELIVQKLLETTDRPDGH
QNNLRSSAYESLMEIVKNSAKDCYPAVQKTTLVIMERLQQ
VLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDA
LQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLG
GEFLKYMEAFKPFLGIGLKNYAEYQVCLAAVGLVGDLCRA
LQSNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDI
ALAIGGEFKKYLEVVLNTLQQASQAQVDKSDYDMVDYLNE
LRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSF
IDHIAGDEDHTDGVVACAAGLIGDLCTAFGKDVLKLVEAR
PMIHELLTEGRRSKTNKAKTLATWATKELRKLK
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| C: |
DHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGEN
ADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAK
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Description
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Functional site
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1)
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chain |
B |
| residue |
835 |
| type |
MOD_RES |
| sequence |
K
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| description |
Deamidated asparagine; partial => ECO:0000269|PubMed:9582379
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| source |
Swiss-Prot : SWS_FT_FI3
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2)
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chain |
B |
| residue |
867 |
| type |
MOD_RES |
| sequence |
K
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| description |
Deamidated asparagine; partial => ECO:0000269|PubMed:9582379
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| source |
Swiss-Prot : SWS_FT_FI3
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3)
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chain |
C |
| residue |
42 |
| type |
MOD_RES |
| sequence |
R
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| description |
Citrulline => ECO:0000250|UniProtKB:P43275
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| source |
Swiss-Prot : SWS_FT_FI4
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