eF-site ID 6n6j-B
PDB Code 6n6j
Chain B

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Title Human REXO2 bound to pAA
Classification rna binding protein/rna
Compound RNA exonuclease 2 homolog,Small fragment nuclease
Source (6N6J)
Sequence B:  AAGESMAQRMVWVDLEMTGLDIEKDQIIEMACLITDSDLN
ILAEGPNLIIKQPDELLDSMSDWCKEHHGKSGLTKAVKES
TITLQQAEYEFLSFVRQQTPPGLCPLAGNSVHEDKKFLDK
YMPQFMKHLHYRIIDVSTVKELCRRWYPEEYEFAPKKAAS
HRALDDISESIKELQFYRNNIFKKKI
Description


Functional site

1) chain B
residue 97
type
sequence R
description binding site for residue MLI A 302
source : AC2

2) chain B
residue 102
type
sequence P
description binding site for residue MLI A 302
source : AC2

3) chain B
residue 151
type
sequence E
description binding site for residue MLI A 302
source : AC2

4) chain B
residue 45
type
sequence E
description binding site for residue GOL B 301
source : AC4

5) chain B
residue 169
type
sequence S
description binding site for residue GOL B 301
source : AC4

6) chain B
residue 110
type
sequence N
description binding site for residue EDO C 701
source : AC5

7) chain B
residue 167
type
sequence D
description binding site for residue EDO C 701
source : AC5

8) chain B
residue 15
type
sequence D
description binding site for residue NA C 702
source : AC6

9) chain B
residue 47
type BINDING
sequence P
description BINDING => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:31588022, ECO:0007744|PDB:6J7Y, ECO:0007744|PDB:6RCN
source Swiss-Prot : SWS_FT_FI2

10) chain B
residue 49
type BINDING
sequence L
description BINDING => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:31588022, ECO:0007744|PDB:6J7Y, ECO:0007744|PDB:6RCN
source Swiss-Prot : SWS_FT_FI2

11) chain B
residue 147
type BINDING
sequence W
description BINDING => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:31588022, ECO:0007744|PDB:6RCN
source Swiss-Prot : SWS_FT_FI3

12) chain B
residue 53
type SITE
sequence Q
description Important for dinucleotide binding => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:32365187
source Swiss-Prot : SWS_FT_FI5

13) chain B
residue 96
type SITE
sequence V
description Important for dinucleotide binding => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:32365187
source Swiss-Prot : SWS_FT_FI5

14) chain B
residue 164
type SITE
sequence A
description Important for dinucleotide binding => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:32365187
source Swiss-Prot : SWS_FT_FI5

15) chain B
residue 92
type MOD_RES
sequence F
description Phosphoserine => ECO:0007744|PubMed:24275569
source Swiss-Prot : SWS_FT_FI6

16) chain B
residue 122
type MOD_RES
sequence Y
description Phosphotyrosine => ECO:0007744|PubMed:15592455
source Swiss-Prot : SWS_FT_FI7

17) chain B
residue 173
type MOD_RES
sequence K
description N6-acetyllysine => ECO:0000250|UniProtKB:Q9D8S4
source Swiss-Prot : SWS_FT_FI8


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