eF-site ID 6n6j-AB PDB Code 6n6j Chain A, B click to enlarge Title Human REXO2 bound to pAA Classification rna binding protein/rna Compound RNA exonuclease 2 homolog,Small fragment nuclease Source (6N6J) Sequence A:  GESMAQRMVWVDLEMTGLDIEKDQIIEMACLITDSDLNIL AEGPNLIIKQPDELLDSMSDWCKEHHGKSGLTKAVKESTI TLQQAEYEFLSFVRQQTPPGLCPLAGNSVHEDKKFLDKYM PQFMKHLHYRIIDVSTVKELCRRWYPEEYEFAPKKAASHR ALDDISESIKELQFYRNNIFKKKIDEKKRKIIENG B:  AAGESMAQRMVWVDLEMTGLDIEKDQIIEMACLITDSDLN ILAEGPNLIIKQPDELLDSMSDWCKEHHGKSGLTKAVKES TITLQQAEYEFLSFVRQQTPPGLCPLAGNSVHEDKKFLDK YMPQFMKHLHYRIIDVSTVKELCRRWYPEEYEFAPKKAAS HRALDDISESIKELQFYRNNIFKKKI Description Functional site 1) chain A residue 110 type sequence N description binding site for residue GOL A 301 source : AC1 2) chain A residue 158 type sequence K description binding site for residue GOL A 301 source : AC1 3) chain A residue 160 type sequence A description binding site for residue GOL A 301 source : AC1 4) chain A residue 162 type sequence H description binding site for residue GOL A 301 source : AC1 5) chain A residue 167 type sequence D description binding site for residue GOL A 301 source : AC1 6) chain A residue 186 type sequence K description binding site for residue MLI A 302 source : AC2 7) chain A residue 187 type sequence I description binding site for residue MLI A 302 source : AC2 8) chain B residue 97 type sequence R description binding site for residue MLI A 302 source : AC2 9) chain B residue 102 type sequence P description binding site for residue MLI A 302 source : AC2 10) chain B residue 151 type sequence E description binding site for residue MLI A 302 source : AC2 11) chain A residue 15 type sequence D description binding site for residue NA D 701 source : AC3 12) chain A residue 86 type sequence Q description binding site for residue GOL B 301 source : AC4 13) chain A residue 89 type sequence E description binding site for residue GOL B 301 source : AC4 14) chain A residue 124 type sequence P description binding site for residue GOL B 301 source : AC4 15) chain A residue 125 type sequence Q description binding site for residue GOL B 301 source : AC4 16) chain B residue 45 type sequence E description binding site for residue GOL B 301 source : AC4 17) chain B residue 169 type sequence S description binding site for residue GOL B 301 source : AC4 18) chain B residue 110 type sequence N description binding site for residue EDO C 701 source : AC5 19) chain B residue 167 type sequence D description binding site for residue EDO C 701 source : AC5 20) chain B residue 15 type sequence D description binding site for residue NA C 702 source : AC6 21) chain A residue 194 type ACT_SITE sequence I description ACT_SITE => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:31588022 source Swiss-Prot : SWS_FT_FI1 22) chain A residue 47 type BINDING sequence P description BINDING => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:31588022, ECO:0007744|PDB:6J7Y, ECO:0007744|PDB:6RCN source Swiss-Prot : SWS_FT_FI2 23) chain A residue 49 type BINDING sequence L description BINDING => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:31588022, ECO:0007744|PDB:6J7Y, ECO:0007744|PDB:6RCN source Swiss-Prot : SWS_FT_FI2 24) chain B residue 47 type BINDING sequence P description BINDING => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:31588022, ECO:0007744|PDB:6J7Y, ECO:0007744|PDB:6RCN source Swiss-Prot : SWS_FT_FI2 25) chain B residue 49 type BINDING sequence L description BINDING => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:31588022, ECO:0007744|PDB:6J7Y, ECO:0007744|PDB:6RCN source Swiss-Prot : SWS_FT_FI2 26) chain A residue 147 type BINDING sequence W description BINDING => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:31588022, ECO:0007744|PDB:6RCN source Swiss-Prot : SWS_FT_FI3 27) chain B residue 147 type BINDING sequence W description BINDING => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:31588022, ECO:0007744|PDB:6RCN source Swiss-Prot : SWS_FT_FI3 28) chain A residue 53 type SITE sequence Q description Important for dinucleotide binding => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:32365187 source Swiss-Prot : SWS_FT_FI5 29) chain A residue 96 type SITE sequence V description Important for dinucleotide binding => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:32365187 source Swiss-Prot : SWS_FT_FI5 30) chain A residue 164 type SITE sequence A description Important for dinucleotide binding => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:32365187 source Swiss-Prot : SWS_FT_FI5 31) chain B residue 53 type SITE sequence Q description Important for dinucleotide binding => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:32365187 source Swiss-Prot : SWS_FT_FI5 32) chain B residue 96 type SITE sequence V description Important for dinucleotide binding => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:32365187 source Swiss-Prot : SWS_FT_FI5 33) chain B residue 164 type SITE sequence A description Important for dinucleotide binding => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:32365187 source Swiss-Prot : SWS_FT_FI5 34) chain A residue 92 type MOD_RES sequence F description Phosphoserine => ECO:0007744|PubMed:24275569 source Swiss-Prot : SWS_FT_FI6 35) chain B residue 92 type MOD_RES sequence F description Phosphoserine => ECO:0007744|PubMed:24275569 source Swiss-Prot : SWS_FT_FI6 36) chain A residue 122 type MOD_RES sequence Y description Phosphotyrosine => ECO:0007744|PubMed:15592455 source Swiss-Prot : SWS_FT_FI7 37) chain B residue 122 type MOD_RES sequence Y description Phosphotyrosine => ECO:0007744|PubMed:15592455 source Swiss-Prot : SWS_FT_FI7 38) chain A residue 173 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:Q9D8S4 source Swiss-Prot : SWS_FT_FI8 39) chain B residue 173 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:Q9D8S4 source Swiss-Prot : SWS_FT_FI8

Display surface Download Links