eF-site ID 6n6i-ABCD PDB Code 6n6i Chain A, B, C, D click to enlarge Title Human REXO2 bound to pGG Classification rna binding protein/rna Compound RNA exonuclease 2 homolog,Small fragment nuclease Source (6N6I) Sequence A:  GESMAQRMVWVDLEMTGLDIEKDQIIEMACLITDSDLNIL AEGPNLIIKQPDELLDSMSDWCKEHHGKSGLTKAVKESTI TLQQAEYEFLSFVRQQTPPGLCPLAGNSVHEDKKFLDKYM PQFMKHLHYRIIDVSTVKELCRRWYPEEYEFAPKKAASHR ALDDISESIKELQFYRNNIFKKK B:  AAGESMAQRMVWVDLEMTGLDIEKDQIIEMACLITDSDLN ILAEGPNLIIKQPDELLDSMSDWCKEHHGKSGLTKAVKES TITLQQAEYEFLSFVRQQTPPGLCPLAGNSVHEDKKFLDK YMPQFMKHLHYRIIDVSTVKELCRRWYPEEYEFAPKKAAS HRALDDISESIKELQFYRNNIFKKKI C:  GG D:  GG Description Functional site 1) chain A residue 110 type sequence N description binding site for residue GOL A 301 source : AC1 2) chain A residue 158 type sequence K description binding site for residue GOL A 301 source : AC1 3) chain A residue 160 type sequence A description binding site for residue GOL A 301 source : AC1 4) chain A residue 162 type sequence H description binding site for residue GOL A 301 source : AC1 5) chain A residue 167 type sequence D description binding site for residue GOL A 301 source : AC1 6) chain D residue 603 type sequence G description binding site for residue GOL A 301 source : AC1 7) chain D residue 604 type sequence G description binding site for residue GOL A 301 source : AC1 8) chain A residue 15 type sequence D description binding site for residue NA D 701 source : AC2 9) chain D residue 603 type sequence G description binding site for residue NA D 701 source : AC2 10) chain D residue 604 type sequence G description binding site for residue NA D 701 source : AC2 11) chain A residue 86 type sequence Q description binding site for residue GOL B 301 source : AC3 12) chain A residue 89 type sequence E description binding site for residue GOL B 301 source : AC3 13) chain A residue 124 type sequence P description binding site for residue GOL B 301 source : AC3 14) chain A residue 125 type sequence Q description binding site for residue GOL B 301 source : AC3 15) chain B residue 45 type sequence E description binding site for residue GOL B 301 source : AC3 16) chain B residue 169 type sequence S description binding site for residue GOL B 301 source : AC3 17) chain A residue 186 type sequence K description binding site for residue MLI B 302 source : AC4 18) chain B residue 97 type sequence R description binding site for residue MLI B 302 source : AC4 19) chain B residue 102 type sequence P description binding site for residue MLI B 302 source : AC4 20) chain B residue 151 type sequence E description binding site for residue MLI B 302 source : AC4 21) chain B residue 110 type sequence N description binding site for residue EDO C 701 source : AC5 22) chain B residue 167 type sequence D description binding site for residue EDO C 701 source : AC5 23) chain C residue 603 type sequence G description binding site for residue EDO C 701 source : AC5 24) chain C residue 604 type sequence G description binding site for residue EDO C 701 source : AC5 25) chain B residue 15 type sequence D description binding site for residue NA C 702 source : AC6 26) chain C residue 603 type sequence G description binding site for residue NA C 702 source : AC6 27) chain C residue 604 type sequence G description binding site for residue NA C 702 source : AC6 28) chain A residue 173 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:Q9D8S4 source Swiss-Prot : SWS_FT_FI8 29) chain B residue 173 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:Q9D8S4 source Swiss-Prot : SWS_FT_FI8 30) chain B residue 47 type BINDING sequence P description BINDING => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:31588022, ECO:0007744|PDB:6J7Y, ECO:0007744|PDB:6RCN source Swiss-Prot : SWS_FT_FI2 31) chain B residue 49 type BINDING sequence L description BINDING => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:31588022, ECO:0007744|PDB:6J7Y, ECO:0007744|PDB:6RCN source Swiss-Prot : SWS_FT_FI2 32) chain A residue 47 type BINDING sequence P description BINDING => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:31588022, ECO:0007744|PDB:6J7Y, ECO:0007744|PDB:6RCN source Swiss-Prot : SWS_FT_FI2 33) chain A residue 49 type BINDING sequence L description BINDING => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:31588022, ECO:0007744|PDB:6J7Y, ECO:0007744|PDB:6RCN source Swiss-Prot : SWS_FT_FI2 34) chain A residue 147 type BINDING sequence W description BINDING => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:31588022, ECO:0007744|PDB:6RCN source Swiss-Prot : SWS_FT_FI3 35) chain B residue 147 type BINDING sequence W description BINDING => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:31588022, ECO:0007744|PDB:6RCN source Swiss-Prot : SWS_FT_FI3 36) chain A residue 164 type SITE sequence A description Important for dinucleotide binding => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:32365187 source Swiss-Prot : SWS_FT_FI5 37) chain B residue 53 type SITE sequence Q description Important for dinucleotide binding => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:32365187 source Swiss-Prot : SWS_FT_FI5 38) chain B residue 96 type SITE sequence V description Important for dinucleotide binding => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:32365187 source Swiss-Prot : SWS_FT_FI5 39) chain B residue 164 type SITE sequence A description Important for dinucleotide binding => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:32365187 source Swiss-Prot : SWS_FT_FI5 40) chain A residue 53 type SITE sequence Q description Important for dinucleotide binding => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:32365187 source Swiss-Prot : SWS_FT_FI5 41) chain A residue 96 type SITE sequence V description Important for dinucleotide binding => ECO:0000269|PubMed:30926754, ECO:0000269|PubMed:32365187 source Swiss-Prot : SWS_FT_FI5 42) chain A residue 92 type MOD_RES sequence F description Phosphoserine => ECO:0007744|PubMed:24275569 source Swiss-Prot : SWS_FT_FI6 43) chain B residue 92 type MOD_RES sequence F description Phosphoserine => ECO:0007744|PubMed:24275569 source Swiss-Prot : SWS_FT_FI6 44) chain A residue 122 type MOD_RES sequence Y description Phosphotyrosine => ECO:0007744|PubMed:15592455 source Swiss-Prot : SWS_FT_FI7 45) chain B residue 122 type MOD_RES sequence Y description Phosphotyrosine => ECO:0007744|PubMed:15592455 source Swiss-Prot : SWS_FT_FI7

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