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eF-site ID
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6n60-C |
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PDB Code
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6n60 |
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Chain
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C |
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click to enlarge
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Title
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Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA and Microcin J25 (MccJ25) |
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Classification
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TRANSFERASE/DNA |
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Compound
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DNA-directed RNA polymerase subunit alpha |
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Source
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(6N60) |
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Sequence
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C: |
YSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQD
PEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDV
QECQIRGVTYSAPLRVKLRLVIYERGTVKDIKEQEVYMGE
IPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHS
SGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPA
TIILRALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERL
RGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIE
VPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLS
QSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEI
YRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFN
RSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDID
HLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDT
LMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITH
KRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEG
PNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYL
SAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGESSLFS
RDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQ
RQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQY
VDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCIN
QMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMP
WNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLG
PEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGK
VTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSG
TVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQI
LEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEE
KQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGV
LKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMP
YDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGD
KINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSD
EEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPT
SGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHAR
STGSYSLVTQQPLGGAQFGGQRFGEMEVWALEAYGAAYTL
QEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLL
KEIRSLGINIELEDE
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Description
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Functional site
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1)
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chain |
C |
| residue |
1063-1075 |
| type |
prosite |
| sequence |
GDKMAGRHGNKGV
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| description |
RNA_POL_BETA RNA polymerases beta chain signature. GdKMAGrHGNKGV
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| source |
prosite : PS01166
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