|
|
eF-site ID
|
6n5e-ADE |
|
PDB Code
|
6n5e |
|
Chain
|
A, D, E |
|
click to enlarge
|
|
|
Title
|
Broadly protective antibodies directed to a subdominant influenza hemagglutinin epitope |
|
Classification
|
VIRAL PROTEIN/IMMUNE SYSTEM |
|
Compound
|
Hemagglutinin |
|
Source
|
(6N5E) |
|
|
Sequence
|
A: |
TNATELVQSSSTGKICNNPHRILDGIDCTLIDALLGDPHC
DVFQNETWDLFVERSKAFSNCYPYDVPDYASLRSLVASSG
TLEFITEGFTWTGVTQNGGSNACKRGPGSGFFSRLNWLTK
SGSTYPVLNVTMPNNDNFDKLYIWGIHHPSTDQEQTSLYV
QASGRVTVSTRRSQQTIIPNIGSRPWVRGLSSRISIYWTI
VKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDT
CISECITPNGSIPNDKPFQNVNKITYGACPKYVKQNTLKL
AT
|
| D: |
QAVVTQESALTTSPGETVTLTCRSSTGAVTTSNYANWVQE
KPDHLFTGLIGGTNNRAPGVPARFSGSLIGDKAALTITGA
QTEDEAIYFCALWFSNHWVFGGGTKLTVLGQPKGAPSVTL
FPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKA
GVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTH
EGSTVEKTVAP
|
| E: |
DVKLVESGEGLVKPGGSLKLSCAASGFTFSGYDMSWVRQT
PEKRLEWVAYISSGGDYIYYADTVKGRFTISRDNARNTLY
LQMSSLKSEDTAMYYCTRDSDYYGSRVWFAYWGQGTLVTV
SGASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVT
VSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGT
QTYICNVNHKPSNTKVDKRVEPKSCD
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
38 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04072
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
A |
| residue |
81 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04072
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
A |
| residue |
165 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04072
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
A |
| residue |
285 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04072
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|