eF-site ID 6mvq-A PDB Code 6mvq Chain A click to enlarge Title HCV NS5B 1b N316 bound to Compound 31 Classification VIRAL PROTEIN Compound HCV Polymerase Source (Q99AU2_9HEPC) Sequence A:  SMSYTWTGALITPCAAEESKLPINALSNSLLRHHNMVYAT TSRSAGQRQKKVTFDRLQVLDDHYRDVLKEMKAKASTVKA KLLSVEEACKLTPPHSAKSKYGYGAKDVRNLSSRAVNHIH SVWKDLLEDTVTPIDTTIMAKNEVFCVQRKPARLIVFPDL GVRVCEKMALYDVVSTLPQVVMGSSYGFQYSPGQRVEFLV NTWKSKKNPMGFSYDTRCFDSTVTENDIRVEESIYQCCDL APEARQAIKSLTERLYIGGPLTNSKGQNCGYRRCRASGVL TTSCGNTLTCYLKASAACRAAKLQDCTMLVNGDDLVVICE SAGVQEDAASLRVFTEAMTRYSAPPGDPPQPEYDLELITS CSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETARHTPV NSWLGNIIMYAPTLWARMILMTHFFSILLAQEQLEKALDC QIYGACYSIEPLDLPQIIERLHGLSAFSLHSYSPGEINRV ASCLRKLGVPPLRVWRHRARSVRARLLSQGGRAATCGKYL FNWAVKTKLKLTPIDLSGWFVAGYSGGDIYHA Description Functional site 1) chain A residue 193 type sequence F description binding site for residue K4M A 601 source : AC1 2) chain A residue 200 type sequence R description binding site for residue K4M A 601 source : AC1 3) chain A residue 204 type sequence L description binding site for residue K4M A 601 source : AC1 4) chain A residue 314 type sequence L description binding site for residue K4M A 601 source : AC1 5) chain A residue 316 type sequence N description binding site for residue K4M A 601 source : AC1 6) chain A residue 319 type sequence D description binding site for residue K4M A 601 source : AC1 7) chain A residue 321 type sequence V description binding site for residue K4M A 601 source : AC1 8) chain A residue 363 type sequence I description binding site for residue K4M A 601 source : AC1 9) chain A residue 365 type sequence S description binding site for residue K4M A 601 source : AC1 10) chain A residue 368 type sequence S description binding site for residue K4M A 601 source : AC1 11) chain A residue 384 type sequence L description binding site for residue K4M A 601 source : AC1 12) chain A residue 414 type sequence M description binding site for residue K4M A 601 source : AC1 13) chain A residue 415 type sequence Y description binding site for residue K4M A 601 source : AC1 14) chain A residue 448 type sequence Y description binding site for residue K4M A 601 source : AC1

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