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eF-site ID
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6mu7-G |
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PDB Code
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6mu7 |
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Chain
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G |
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click to enlarge
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Title
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Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to Small Molecule HIV-1 Entry Inhibitor BMS-818251 in Complex with Human Antibodies 3H109L and 35O22 at 3.1 Angstrom |
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Classification
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IMMUNE SYSTEM/INHIBITOR |
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Compound
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Envelope glycoprotein gp160 |
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Source
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(6MU7) |
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Sequence
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G: |
ENLWVTVYYGVPVWKDAETTLFCASDAKAKHNVWATHACV
PTDPNPQEIHLENVTEEFNMWKNNMVEQMHTDIISLWDQS
LKPCVKLTPLCVTLQCTNVTNAITDDMRGELKNCSFNMTT
ELRDKKQKVYSLFYRLDVVQINNKEYRLINCNTSAITQAC
PKVSFEPIPIHYCAPAGFAILKCKDKKFNGTGPCPSVSTV
QCTHGIKPVVSTQLLLNGSLAEEEVMIRSENITNNAKNIL
VQFNTPVQINCTRPNNNTRKSIRIGPGQAFYATGDIIGDI
RQAHCNVSKATWNETLGKVVKQLRKHFGNNTIIRFANSSG
GDLEVTTHSFNCGGEFFYCNTSGLFNSTWISNGSNDSITL
PCRIKQIINMWQRIGQAMYAPPIQGVIRCVSNITGLILTR
DGTETFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTRCK
RR
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Description
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(1) |
Envelope glycoprotein gp160, 35O22 scFv heavy chain portion, 35O22 scFv light chain portion, 3H109L Fab heavy chain, 3H109L Fab light chain
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