eF-site ID 6mtg-B PDB Code 6mtg Chain B click to enlarge Title A Single Reactive Noncanonical Amino Acid is Able to Dramatically Stabilize Protein Structure Classification TRANSFERASE Compound Homoserine O-succinyltransferase Source (METAS_ECOLI) Sequence B:  PIRVPDELPAVNFLREENVFVMTTSRAEIRPLKVLILNLM PKKIETENQFLRLLSNSPLQVDIQLLRIDSRESRNTPAEH LNNFYCNFEDIQDQNFDGLIVTGAPLGLVEFNDVAYWPQI KQVLEWSKDHVTSTLFVXWAVQAALNILYGIPKQTRTEKL SGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRD YTDLEILAETEEGDAYLFASKDKRIAFVTGHPEYDAQTLA QEFFRDVEAGLDIDVPYNYFPHNDPQNTPRASWRSHGNLL FTNWLNYYVYQI Description Functional site 1) chain B residue 152 type sequence L description binding site for residue PEG A 401 source : AC1 2) chain B residue 153 type sequence Y description binding site for residue PEG A 401 source : AC1 3) chain B residue 154 type sequence G description binding site for residue PEG A 401 source : AC1 4) chain B residue 56 type sequence R description binding site for residue PEG A 402 source : AC2 5) chain B residue 59 type sequence S description binding site for residue PEG A 402 source : AC2 6) chain B residue 60 type sequence N description binding site for residue PEG A 402 source : AC2 7) chain B residue 47 type sequence K description binding site for residue FMT A 404 source : AC4 8) chain B residue 78 type sequence R description binding site for residue FMT A 404 source : AC4 9) chain B residue 173 type sequence L description binding site for residue GOL B 401 source : AC5 10) chain B residue 174 type sequence H description binding site for residue GOL B 401 source : AC5 11) chain B residue 209 type sequence E description binding site for residue GOL B 401 source : AC5 12) chain B residue 210 type sequence I description binding site for residue GOL B 401 source : AC5 13) chain B residue 177 type sequence A description binding site for residue FMT B 402 source : AC6 14) chain B residue 178 type sequence L description binding site for residue FMT B 402 source : AC6 15) chain B residue 179 type sequence L description binding site for residue FMT B 402 source : AC6 16) chain B residue 292 type sequence Y description binding site for residue FMT B 402 source : AC6 17) chain B residue 107 type sequence G description binding site for residue FMT B 403 source : AC7 18) chain B residue 108 type sequence A description binding site for residue FMT B 403 source : AC7 19) chain B residue 142 type sequence X description binding site for residue FMT B 403 source : AC7 20) chain B residue 143 type sequence W description binding site for residue FMT B 403 source : AC7 21) chain B residue 235 type sequence H description binding site for residue FMT B 403 source : AC7 22) chain B residue 8 type sequence E description binding site for residue FMT B 404 source : AC8 23) chain B residue 117 type sequence D description binding site for residue FMT B 404 source : AC8 24) chain B residue 142 type ACT_SITE sequence X description Acyl-thioester intermediate => ECO:0000255|HAMAP-Rule:MF_00295, ECO:0000305|PubMed:10572016, ECO:0000305|PubMed:17302437, ECO:0000305|PubMed:17442255 source Swiss-Prot : SWS_FT_FI1 25) chain B residue 235 type ACT_SITE sequence H description Proton acceptor => ECO:0000255|HAMAP-Rule:MF_00295, ECO:0000305|PubMed:17302437, ECO:0000305|PubMed:17442255 source Swiss-Prot : SWS_FT_FI2 26) chain B residue 237 type ACT_SITE sequence E description ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00295, ECO:0000305|PubMed:17302437, ECO:0000305|PubMed:17442255 source Swiss-Prot : SWS_FT_FI3 27) chain B residue 111 type SITE sequence G description Important for acyl-CoA specificity => ECO:0000255|HAMAP-Rule:MF_00295 source Swiss-Prot : SWS_FT_FI5 28) chain B residue 163 type BINDING sequence K description BINDING => ECO:0000255|HAMAP-Rule:MF_00295 source Swiss-Prot : SWS_FT_FI4 29) chain B residue 192 type BINDING sequence S description BINDING => ECO:0000255|HAMAP-Rule:MF_00295 source Swiss-Prot : SWS_FT_FI4 30) chain B residue 249 type BINDING sequence R description BINDING => ECO:0000255|HAMAP-Rule:MF_00295 source Swiss-Prot : SWS_FT_FI4 31) chain B residue 192 type SITE sequence S description Important for substrate specificity => ECO:0000255|HAMAP-Rule:MF_00295 source Swiss-Prot : SWS_FT_FI6

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