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eF-site ID
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6msj-U |
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PDB Code
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6msj |
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Chain
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U |
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click to enlarge
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Title
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Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome |
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Classification
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HYDROLASE |
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Compound
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26S proteasome non-ATPase regulatory subunit 1 |
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Source
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(PSA6_HUMAN) |
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Sequence
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U: |
GIISLLDEDEPQLKEFALHKLNAVVNDFWAEISESVDKIE
VLYEDEGFRSRQFAALVASKVFYHLGAFEESLNYALGAGD
LFNVNDNSEYVETIIAKCIDHYTKQCVENADLPEGEKKPI
DQRLEGIVNKMFQRCLDDHKYKQAIGIALETRRLDVFEKT
ILESNDVPGMLAYSLKLCMSLMQNKQFRNKVLRVLVKIYM
NLEKPDFINVCQCLIFLDDPQAVSDILEKLVKEDNLLMAY
QICFDLYESASQQFLSSVIQNLRTDQTLKMIKILSGEMAI
ELHLQFLIRNNNTDLMILKNTKDAVRNSVCHTATVIANSF
MHCGTTSDQFLRDNLEWLARATNWAKFTATASLGVIHKGH
EKEALQLMATYLPKDTSPGSAYQEGGGLYALGLIHANHGG
DIIDYLLNQLKNASNDIVRHGGSLGLGLAAMGTARQDVYD
LLKTNLYQDDAVTGEAAGLALGLVMLGSKNAQAIEDMVGY
AQETQHEKILRGLAVGIALVMYGRMEEADALIESLCRDKD
PILRRSGMYTVAMAYCGSGNNKAIRRLLHVAVSDVNDDVR
RAAVESLGFILFRTPEQCPSVVSLLSESYNPHVRYGAAMA
LGICCAGTGNKEAINLLEPMTNDPVNYVRQGALIASALIM
IQQTEITCPKVNQFRQLYSKVINDKHDDVMAKFGAILAQG
ILDAGGHNVTISLQSRTGHTHMPSVVGVLVFTQFWFWFPL
SHFLSLAYTPTCVIGLNKDLKMPKVQYKSNCKPSTFAYPA
PLEVPKEKEKEKVSTAVLSITAKAKKKEKEKEKKEEEKME
VDEAEKKEEKEKKKEPEPNFQLLDNPARVMPAQLKVLTMP
ETCRYQPFKPLSIGGIIILKDTSEDIEELVEP
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Description
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(1) |
26S proteasome
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