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eF-site ID
|
6msj-F |
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PDB Code
|
6msj |
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Chain
|
F |
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click to enlarge
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Title
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Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome |
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Classification
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HYDROLASE |
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Compound
|
26S proteasome non-ATPase regulatory subunit 1 |
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Source
|
(PSA6_HUMAN) |
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Sequence
|
F: |
EQDGIGEEVLKMSTEEIIQRTRLLDSEIKIMKSEVLRVTH
ELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVKCAVI
KTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETL
PTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVL
PMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQT
KATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIF
IDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNT
QVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARAR
IMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAG
MIALRRGATELTHEDYMEGILEVQAKKKANLQYYA
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Description
|
(1) |
26S proteasome
|
|
Functional site
|
|
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1)
|
chain |
F |
| residue |
344 |
| type |
|
| sequence |
R
|
| description |
binding site for residue ADP E 419
|
| source |
: AD1
|
|
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2)
|
chain |
F |
| residue |
326-344 |
| type |
prosite |
| sequence |
VKVIAATNRVDILDPALLR
|
| description |
AAA AAA-protein family signature. IkVImATNridiLDsALl.R
|
| source |
prosite : PS00674
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