eF-site ID 6msj-C PDB Code 6msj Chain C click to enlarge Title Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome Classification HYDROLASE Compound 26S proteasome non-ATPase regulatory subunit 1 Source (PSA6_HUMAN) Sequence C:  LEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRN ELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVH PEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNK VDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVK HPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCT FIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDE IDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIK VIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILK IHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYA LRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK Description (1)  26S proteasome Functional site 1) chain C residue 307 type sequence R description binding site for residue ATP B 441 source : AC4 2) chain C residue 151 type sequence I description binding site for residue ATP C 407 source : AC6 3) chain C residue 154 type sequence L description binding site for residue ATP C 407 source : AC6 4) chain C residue 193 type sequence G description binding site for residue ATP C 407 source : AC6 5) chain C residue 194 type sequence T description binding site for residue ATP C 407 source : AC6 6) chain C residue 195 type sequence G description binding site for residue ATP C 407 source : AC6 7) chain C residue 196 type sequence K description binding site for residue ATP C 407 source : AC6 8) chain C residue 197 type sequence T description binding site for residue ATP C 407 source : AC6 9) chain C residue 198 type sequence L description binding site for residue ATP C 407 source : AC6 10) chain C residue 250 type sequence E description binding site for residue ATP C 407 source : AC6 11) chain C residue 328 type sequence I description binding site for residue ATP C 407 source : AC6 12) chain C residue 332 type sequence H description binding site for residue ATP C 407 source : AC6 13) chain C residue 356 type sequence G description binding site for residue ATP C 407 source : AC6 14) chain C residue 357 type sequence A description binding site for residue ATP C 407 source : AC6 15) chain C residue 360 type sequence K description binding site for residue ATP C 407 source : AC6 16) chain C residue 197 type sequence T description binding site for residue MG C 408 source : AC7 17) chain C residue 250 type sequence E description binding site for residue MG C 408 source : AC7 18) chain C residue 289-307 type prosite sequence IKVIMATNRIDILDSALLR description AAA AAA-protein family signature. VkMImATNrpdtLDpALl.R source prosite : PS00674

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