eF-site ID 6msj-B PDB Code 6msj Chain B click to enlarge Title Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome Classification HYDROLASE Compound 26S proteasome non-ATPase regulatory subunit 1 Source (PSA6_HUMAN) Sequence B:  PTRVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIK DYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSV GTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCS VLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGG LDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPG TGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRE LFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTM LELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDR KIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDD LSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYK KQEGTPEGLYL Description (1)  26S proteasome Functional site 1) chain B residue 343 type sequence R description binding site for residue ATP A 434 source : AC2 2) chain B residue 188 type sequence G description binding site for residue ATP B 441 source : AC4 3) chain B residue 228 type sequence P description binding site for residue ATP B 441 source : AC4 4) chain B residue 229 type sequence G description binding site for residue ATP B 441 source : AC4 5) chain B residue 230 type sequence T description binding site for residue ATP B 441 source : AC4 6) chain B residue 231 type sequence G description binding site for residue ATP B 441 source : AC4 7) chain B residue 232 type sequence K description binding site for residue ATP B 441 source : AC4 8) chain B residue 233 type sequence T description binding site for residue ATP B 441 source : AC4 9) chain B residue 234 type sequence L description binding site for residue ATP B 441 source : AC4 10) chain B residue 332 type sequence N description binding site for residue ATP B 441 source : AC4 11) chain B residue 368 type sequence H description binding site for residue ATP B 441 source : AC4 12) chain B residue 392 type sequence G description binding site for residue ATP B 441 source : AC4 13) chain B residue 393 type sequence A description binding site for residue ATP B 441 source : AC4 14) chain B residue 396 type sequence K description binding site for residue ATP B 441 source : AC4 15) chain B residue 233 type sequence T description binding site for residue MG B 442 source : AC5 16) chain B residue 237 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:17370265 source Swiss-Prot : SWS_FT_FI8 17) chain B residue 325-343 type prosite sequence VKVIMATNRIETLDPALIR description AAA AAA-protein family signature. VkVImATNradtLDpALl.R source prosite : PS00674

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