eF-site ID 6msj-A PDB Code 6msj Chain A click to enlarge Title Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome Classification HYDROLASE Compound 26S proteasome non-ATPase regulatory subunit 1 Source (PSA6_HUMAN) Sequence A:  PIRALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKIN ELTGIKESDTGLAPPALWDLAADKQTLQSEQPLQVARCTK IINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRV GVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGC KEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGT GKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVREL FEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTML ELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRK IEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNS TGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSY AKFSATPRYMTYN Description (1)  26S proteasome Functional site 1) chain A residue 176 type sequence D description binding site for residue ATP A 434 source : AC2 2) chain A residue 218 type sequence P description binding site for residue ATP A 434 source : AC2 3) chain A residue 219 type sequence G description binding site for residue ATP A 434 source : AC2 4) chain A residue 220 type sequence T description binding site for residue ATP A 434 source : AC2 5) chain A residue 221 type sequence G description binding site for residue ATP A 434 source : AC2 6) chain A residue 222 type sequence K description binding site for residue ATP A 434 source : AC2 7) chain A residue 223 type sequence T description binding site for residue ATP A 434 source : AC2 8) chain A residue 224 type sequence L description binding site for residue ATP A 434 source : AC2 9) chain A residue 276 type sequence E description binding site for residue ATP A 434 source : AC2 10) chain A residue 354 type sequence I description binding site for residue ATP A 434 source : AC2 11) chain A residue 358 type sequence H description binding site for residue ATP A 434 source : AC2 12) chain A residue 382 type sequence G description binding site for residue ATP A 434 source : AC2 13) chain A residue 383 type sequence A description binding site for residue ATP A 434 source : AC2 14) chain A residue 223 type sequence T description binding site for residue MG A 435 source : AC3 15) chain A residue 315-333 type prosite sequence IKVLMATNRPDTLDPALMR description AAA AAA-protein family signature. VkVImATNradtLDpALl.R source prosite : PS00674

Display surface Download Links