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eF-site ID
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6msh-f |
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PDB Code
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6msh |
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Chain
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f |
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click to enlarge
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Title
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Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome |
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Classification
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HYDROLASE |
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Compound
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26S proteasome non-ATPase regulatory subunit 1 |
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Source
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(PSB4_HUMAN) |
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Sequence
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f: |
GGRDKAPVQPQQSPAAAPGGTDEKPSGKERRDAGDKDKEQ
ELSEEDKQLQDELEMLVERLGEKDTSLYRPALEELRRQIR
SSTTSMTSVPKPLKFLRPHYGKLKEIYENMAPGENKRFAA
DIISVLAMTMSGERECLKYRLVGSQEELASWGHEYVRHLA
GEVAKEWQELDDAEKVQREPLLTLVKEIVPYNMAHNAEHE
ACDLLMEIEQVDMLEKDIDENAYAKVCLYLTSCVNYVPEP
ENSALLRCALGVFRKFSRFPEALRLALMLNDMELVEDIFT
SCKDVVVQKQMAFMLGRHGVFLELSEDVEEYEDLTEIMSN
VQLNSNFLALARELDIMEPKVPDDIYKTHLENNRFGGSGS
QVDSARMNLASSFVNGFVNAAFGQDKLLTDDGNKWLYKNK
DHGMLSAAASLGMILLWDVDGGLTQIDKYLYSSEDYIKSG
ALLACGIVNSGVRNECDPALALLSDYVLHNSNTMRLGSIF
GLGLAYAGSNREDVLTLLLPVMGDSKSSMEVAGVTALACG
MIAVGSCNGDVTSTILQTIMEKSETELKDTYARWLPLGLG
LNHLGKGEAIEAILAALEVVSEPFRSFANTLVDVCAYAGS
GNVLKVQQLLHICSEHFDSKEKEEDKDKKEKKDKDKKEAP
ADMGAHQGVAVLGIALIAMGEEIGAEMALRTFGHLLRYGE
PTLRRAVPLALALISVSNPRLNILDTLSKFSHDADPEVSY
NSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFMVR
LAQGLTHLGKGTLTLCPYHSDRQLMSQVAVAGLLTVLVSF
LDVRNIILGKSHYVLYGLVAAMQPRMLVTFDEELRPLPVS
VRVGQAVDVVGQAGKPKTITGFQTHTTPVLLAHGERAELA
TEEFLP
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Description
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(1) |
26S proteasome
|
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Functional site
|
|
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1)
|
chain |
f |
| residue |
551 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0000250|UniProtKB:Q8VDM4
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| source |
Swiss-Prot : SWS_FT_FI9
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