|
eF-site ID
|
6msh-c |
PDB Code
|
6msh |
Chain
|
c |
|
click to enlarge
|
|
Title
|
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome |
Classification
|
HYDROLASE |
Compound
|
26S proteasome non-ATPase regulatory subunit 1 |
Source
|
(PSB4_HUMAN) |
|
Sequence
|
c: |
AVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVD
DYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTG
RPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAV
VVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGH
LNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKK
SWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEED
KMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAM
LDTVVFK
|
|
Description
|
(1) |
26S proteasome
|
|
Functional site
|
|
1)
|
chain |
c |
residue |
113 |
type |
|
sequence |
H
|
description |
binding site for residue ZN c 401
|
source |
: AC1
|
|
2)
|
chain |
c |
residue |
115 |
type |
|
sequence |
H
|
description |
binding site for residue ZN c 401
|
source |
: AC1
|
|
3)
|
chain |
c |
residue |
126 |
type |
|
sequence |
D
|
description |
binding site for residue ZN c 401
|
source |
: AC1
|
|
|
|