eF-site ID 6msh-D PDB Code 6msh Chain D click to enlarge Title Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome Classification HYDROLASE Compound 26S proteasome non-ATPase regulatory subunit 1 Source (PSB4_HUMAN) Sequence D:  DLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEE VKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILST IDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQ KPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDP PRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQK YLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQ TGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLD PALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEV DLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKD FEKAYKTVIKKDEQEHEFYK Description (1)  26S proteasome Functional site 1) chain D residue 323 type sequence R description binding site for residue ATP C 501 source : AC2 2) chain D residue 326 type sequence R description binding site for residue ATP C 501 source : AC2 3) chain D residue 167 type sequence I description binding site for residue ATP D 501 source : AC3 4) chain D residue 168 type sequence G description binding site for residue ATP D 501 source : AC3 5) chain D residue 208 type sequence P description binding site for residue ATP D 501 source : AC3 6) chain D residue 209 type sequence G description binding site for residue ATP D 501 source : AC3 7) chain D residue 210 type sequence C description binding site for residue ATP D 501 source : AC3 8) chain D residue 211 type sequence G description binding site for residue ATP D 501 source : AC3 9) chain D residue 212 type sequence K description binding site for residue ATP D 501 source : AC3 10) chain D residue 213 type sequence T description binding site for residue ATP D 501 source : AC3 11) chain D residue 214 type sequence M description binding site for residue ATP D 501 source : AC3 12) chain D residue 373 type sequence A description binding site for residue ATP D 501 source : AC3 13) chain D residue 376 type sequence N description binding site for residue ATP D 501 source : AC3 14) chain D residue 305-323 type prosite sequence VKVIMATNRADTLDPALLR description AAA AAA-protein family signature. IkVImATNridiLDsALl.R source prosite : PS00674

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