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eF-site ID
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6msh-B |
|
PDB Code
|
6msh |
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Chain
|
B |
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click to enlarge
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Title
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Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome |
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Classification
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HYDROLASE |
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Compound
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26S proteasome non-ATPase regulatory subunit 1 |
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Source
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(PSB4_HUMAN) |
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Sequence
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B: |
KQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSE
HYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPL
VTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEY
YEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRV
VGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAI
GTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMA
TNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTS
RMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRER
RMKVTNEDFKKSKENVLYKKQEGTPEGLYL
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Description
|
(1) |
26S proteasome
|
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Functional site
|
|
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1)
|
chain |
B |
| residue |
325-343 |
| type |
prosite |
| sequence |
VKVIMATNRIETLDPALIR
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| description |
AAA AAA-protein family signature. IkVImATNridiLDsALl.R
|
| source |
prosite : PS00674
|
|
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2)
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chain |
B |
| residue |
237 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:17370265
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| source |
Swiss-Prot : SWS_FT_FI8
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