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|
eF-site ID
|
6msg-c |
|
PDB Code
|
6msg |
|
Chain
|
c |
|
click to enlarge
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Title
|
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome |
|
Classification
|
HYDROLASE |
|
Compound
|
26S proteasome non-ATPase regulatory subunit 1 |
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Source
|
(PSB4_HUMAN) |
|
|
Sequence
|
c: |
AVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVD
DYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTG
RPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAV
VVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGH
LNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKK
SWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEED
KMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAM
LDTVVFK
|
|
|
Description
|
(1) |
26S proteasome
|
|
Functional site
|
|
|
1)
|
chain |
c |
| residue |
113 |
| type |
|
| sequence |
H
|
| description |
binding site for residue ZN c 401
|
| source |
: AC1
|
|
|
2)
|
chain |
c |
| residue |
115 |
| type |
|
| sequence |
H
|
| description |
binding site for residue ZN c 401
|
| source |
: AC1
|
|
|
3)
|
chain |
c |
| residue |
126 |
| type |
|
| sequence |
D
|
| description |
binding site for residue ZN c 401
|
| source |
: AC1
|
|
|
|