eF-site ID 6msg-C PDB Code 6msg Chain C click to enlarge Title Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome Classification HYDROLASE Compound 26S proteasome non-ATPase regulatory subunit 1 Source (PSB4_HUMAN) Sequence C:  LEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRRLQAQRN ELNAKVRLLREELQLLQEQGSYVGEVVRAMDKKKVLVKVH PEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNK VDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVK HPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCT FIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDE IDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIK VIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILK IHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYA LRERRVHVTQEDFEMAVAKVMQKDSEKNMSIKKLWK Description (1)  26S proteasome Functional site 1) chain C residue 150 type sequence M description binding site for residue ATP C 501 source : AC3 2) chain C residue 151 type sequence I description binding site for residue ATP C 501 source : AC3 3) chain C residue 192 type sequence P description binding site for residue ATP C 501 source : AC3 4) chain C residue 193 type sequence G description binding site for residue ATP C 501 source : AC3 5) chain C residue 194 type sequence T description binding site for residue ATP C 501 source : AC3 6) chain C residue 195 type sequence G description binding site for residue ATP C 501 source : AC3 7) chain C residue 196 type sequence K description binding site for residue ATP C 501 source : AC3 8) chain C residue 197 type sequence T description binding site for residue ATP C 501 source : AC3 9) chain C residue 198 type sequence L description binding site for residue ATP C 501 source : AC3 10) chain C residue 328 type sequence I description binding site for residue ATP C 501 source : AC3 11) chain C residue 357 type sequence A description binding site for residue ATP C 501 source : AC3 12) chain C residue 360 type sequence K description binding site for residue ATP C 501 source : AC3 13) chain C residue 197 type sequence T description binding site for residue MG C 502 source : AC4 14) chain C residue 289-307 type prosite sequence IKVIMATNRIDILDSALLR description AAA AAA-protein family signature. IkVImATNridiLDsALl.R source prosite : PS00674

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