|
|
eF-site ID
|
6msb-s |
|
PDB Code
|
6msb |
|
Chain
|
s |
|
click to enlarge
|
|
|
Title
|
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome |
|
Classification
|
HYDROLASE |
|
Compound
|
26S proteasome non-ATPase regulatory subunit 1 |
|
Source
|
(PSB4_HUMAN) |
|
|
Sequence
|
s: |
RFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDS
PKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNN
KAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGA
VYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQN
VEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTK
EGIREETVSLRKD
|
|
|
Description
|
(1) |
26S proteasome
|
|
Functional site
|
|
|
1)
|
chain |
s |
| residue |
34 |
| type |
BINDING |
| sequence |
S
|
| description |
BINDING => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
s |
| residue |
40 |
| type |
BINDING |
| sequence |
S
|
| description |
BINDING => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
s |
| residue |
134 |
| type |
BINDING |
| sequence |
S
|
| description |
BINDING => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
s |
| residue |
176 |
| type |
MOD_RES |
| sequence |
K
|
| description |
Phosphoserine => ECO:0007744|PubMed:23186163
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
5)
|
chain |
s |
| residue |
30 |
| type |
CARBOHYD |
| sequence |
S
|
| description |
O-linked (GlcNAc) serine => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
6)
|
chain |
s |
| residue |
181 |
| type |
CARBOHYD |
| sequence |
S
|
| description |
O-linked (GlcNAc) serine => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
|