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eF-site ID
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6msb-f |
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PDB Code
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6msb |
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Chain
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f |
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click to enlarge
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Title
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Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome |
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Classification
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HYDROLASE |
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Compound
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26S proteasome non-ATPase regulatory subunit 1 |
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Source
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(PSB4_HUMAN) |
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Sequence
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f: |
MEEGGRDKAPVQPQQSPAAAPGGTDEKPSGKERRDAGDKD
KEQELSEEDKQLQDELEMLVERLGEKDTSLYRPALEELRR
QIRSSTTSMTSVPKPLKFLRPHYGKLKEIYENMAPGENKR
FAADIISVLAMTMSGERECLKYRLVGSQEELASWGHEYVR
HLAGEVAKEWQELDDAEKVQREPLLTLVKEIVPYNMAHNA
EHEACDLLMEIEQVDMLEKDIDENAYAKVCLYLTSCVNYV
PEPENSALLRCALGVFRKFSRFPEALRLALMLNDMELVED
IFTSCKDVVVQKQMAFMLGRHGVFLELSEDVEEYEDLTEI
MSNVQLNSNFLALARELDIMEPKVPDDIYKTHLENNRFGG
SGSQVDSARMNLASSFVNGFVNAAFGQDKLLTDDGNKWLY
KNKDHGMLSAAASLGMILLWDVDGGLTQIDKYLYSSEDYI
KSGALLACGIVNSGVRNECDPALALLSDYVLHNSNTMRLG
SIFGLGLAYAGSNREDVLTLLLPVMGDSKSSMEVAGVTAL
ACGMIAVGSCNGDVTSTILQTIMEKSETELKDTYARWLPL
GLGLNHLGKGEAIEAILAALEVVSEPFRSFANTLVDVCAY
AGSGNVLKVQQLLHICSEHFDSKEKEEDKDKKEKKDKDKK
EAPADMGAHQGVAVLGIALIAMGEEIGAEMALRTFGHLLR
YGEPTLRRAVPLALALISVSNPRLNILDTLSKFSHDADPE
VSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLF
MVRLAQGLTHLGKGTLTLCPYHSDRQLMSQVAVAGLLTVL
VSFLDVRNIILGKSHYVLYGLVAAMQPRMLVTFDEELRPL
PVSVRVGQAVDVVGQAGKPKTITGFQTHTTPVLLAHGERA
ELATEEFLP
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Description
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(1) |
26S proteasome
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