eF-site ID 6msb-B PDB Code 6msb Chain B click to enlarge Title Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome Classification HYDROLASE Compound 26S proteasome non-ATPase regulatory subunit 1 Source (PSB4_HUMAN) Sequence B:  ASKLPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQM KPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVST SVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMD DTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPL THPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSA TFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFID EIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDV KVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIF QIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLM ALRERRMKVTNEDFKKSKENVLYK Description (1)  26S proteasome Functional site 1) chain B residue 317 type sequence D description binding site for residue ATP A 501 source : AC2 2) chain B residue 343 type sequence R description binding site for residue ATP A 501 source : AC2 3) chain B residue 346 type sequence R description binding site for residue ATP A 501 source : AC2 4) chain B residue 187 type sequence I description binding site for residue ATP B 501 source : AC4 5) chain B residue 228 type sequence P description binding site for residue ATP B 501 source : AC4 6) chain B residue 229 type sequence G description binding site for residue ATP B 501 source : AC4 7) chain B residue 230 type sequence T description binding site for residue ATP B 501 source : AC4 8) chain B residue 231 type sequence G description binding site for residue ATP B 501 source : AC4 9) chain B residue 232 type sequence K description binding site for residue ATP B 501 source : AC4 10) chain B residue 233 type sequence T description binding site for residue ATP B 501 source : AC4 11) chain B residue 234 type sequence L description binding site for residue ATP B 501 source : AC4 12) chain B residue 368 type sequence H description binding site for residue ATP B 501 source : AC4 13) chain B residue 392 type sequence G description binding site for residue ATP B 501 source : AC4 14) chain B residue 393 type sequence A description binding site for residue ATP B 501 source : AC4 15) chain B residue 396 type sequence K description binding site for residue ATP B 501 source : AC4 16) chain B residue 233 type sequence T description binding site for residue MG B 502 source : AC5 17) chain B residue 325-343 type prosite sequence VKVIMATNRIETLDPALIR description AAA AAA-protein family signature. VkVImATNradtLDpALl.R source prosite : PS00674

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