|
Title
|
Cryo-EM structure of Human Parainfluenza Virus Type 3 (hPIV3) in complex with antibody PIA174 |
|
Classification
|
VIRAL PROTEIN/immune system |
|
Compound
|
Fusion glycoprotein F0 |
|
Source
|
(6MJZ) |
|
|
Sequence
|
A: |
IDITKLQHVGVLVNSPKGMKISQNFETRYLILSLIPKIED
SNSCGDQQIKQYKRLLDRLIIPLYDGLKLQKDVIVTATSA
QITAAVALVEAKQAKSDIEKLKEAIRDTNKAVQSVCSSVG
NCIVAIKSVQDYVNKEIVPSIARLGCEAAGLQLGIALTQH
YSELTNCFGDNIGSLQEKGIKLQCIASLYRTNITEIFTTS
TVDKYDIYDLLFTESIKVRVIDVDLNDYSITLQVRLPLLT
RLLNTQIYKVDSISYNIQNREWYIPLPSHIMTKGAFLGGA
DVKECIEAFSSYICPSDPGFVLNHEMESCLSGNISQCPRT
TVTSDIVPRYAFVNGGVVANCITTTCTCNGIGNRINQPPD
QGVKIITHKECNTIGINGMLFNTNKEGTLAFYTPDDITLN
NSVALDPIDISIELNKVKSDLEESKE
|
| B: |
IDITKLQHVGVLVNSPKGMKISQNFETRYLILSLIPKIED
SNSCGDQQIKQYKRLLDRLIIPLYDGLKLQKTSAQITAAV
ALVEAKQAKSDIEKLKEAIRDTNKAVQSVCSSVGNCIVAI
KSVQDYVNKEIVPSIARLGCEAAGLQLGIALTQHYSELTN
CFGIKLQCIASLYRTNITEIFTTSTVDKYDIYDLLFTEKV
RVIDVDLNDYSITLQVRLPLLTRLLNTQIYKVDSISYNIQ
NREWYIPLPSHIMTKGAFLGGADVKECIEAFSSYICPSDP
GFVLNHEMESCLSGNISQCPRTTVTSDIVPRYAFVNGGVV
ANCITTTCTCNGIGNRINQPPDQGVKIITHKECNTIGING
MLFNTNKEGTLAFYTPDDITLNNSVALDPIDISIELNKVK
SDLEESKE
|
| C: |
IDITKLQHVGVLVNSPKGMKISQNFETRYLILSLIPKIED
SNSCGDQQIKQYKRLLDRLIIPLYDTSAQITAAVALVEAK
QAKSDIEKLKEAIRDTNKAVQSVCSSVGNCIVAIKSVQDY
VNKEIVPSIARLGCEAAGLQLGIALTQHYSELTNCFGDNI
GSLQEKGIKLQCIASLYRTNITEIFTTSTVDKYDIYDLLF
TESIKVRVIDVDLNDYSITLQVRLPLLTRLLNTQIYKVDS
ISYNIQNREWYIPLPSHIMTKGAFLGGADVKECIEAFSSY
ICPSDPGFVLNHEMESCLSGNISQCPRTTVTSDIVPRYAF
VNGGVVANCITTTCTCNGIGNRINQPPDQGVKIITHKECN
TIGINGMLFNTNKEGTLAFYTPDDITLNNSVALDPIDISI
ELNKVKSDLEESKEW
|
| H: |
VQLQESGPGLVKPSETLSLTCTVSGGSVSSYYWSWIRQPP
GKGLEWIGNIYYSGTTKYNPSLKSRVTISVDVSKNQFSLN
LISVTAADTAVYFCARQVKSGWFVQPFDYWGQGALVTVSS
|
| L: |
QMTQSPPSLSAYVGDRVTITCRASQAIANYLAWFQQKPGK
APKSLIYAASTLQSGVPSRFSGSGSGTDFTLTISSLQPED
FATYYCHQYNTYPITFGQGTRLEIKRRT
|
|
|
Description
|
(1) |
Fusion glycoprotein F0, PIA174 Fab Heavy chain, PIA174 Fab Light chain
|
