eF-site ID 6md1-B PDB Code 6md1 Chain B click to enlarge Title Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with GW9662 and Oleic acid Classification TRANSCRIPTION Compound Peroxisome proliferator-activated receptor gamma Source (PPARG_HUMAN) Sequence B:  ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSP FVIYDMNSLMMGEDKIKFHIKEVAIRIFQGCQFRSVEAVQ EITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLM NKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKF NALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLL QALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQ VIKKTETHPLLQEIYKD Description Functional site 1) chain B residue 281 type sequence I description binding site for residue OLA B 502 source : AC2 2) chain B residue 287 type sequence F description binding site for residue OLA B 502 source : AC2 3) chain B residue 288 type sequence R description binding site for residue OLA B 502 source : AC2 4) chain B residue 291 type sequence E description binding site for residue OLA B 502 source : AC2 5) chain B residue 341 type sequence I description binding site for residue OLA B 502 source : AC2 6) chain B residue 342 type sequence S description binding site for residue OLA B 502 source : AC2 7) chain B residue 343 type sequence E description binding site for residue OLA B 502 source : AC2 8) chain B residue 364 type sequence M description binding site for residue OLA B 502 source : AC2 9) chain B residue 281 type sequence I description binding site for Di-peptide GW9 B 501 and CYS B 285 source : AC3 10) chain B residue 282 type sequence F description binding site for Di-peptide GW9 B 501 and CYS B 285 source : AC3 11) chain B residue 283 type sequence Q description binding site for Di-peptide GW9 B 501 and CYS B 285 source : AC3 12) chain B residue 284 type sequence G description binding site for Di-peptide GW9 B 501 and CYS B 285 source : AC3 13) chain B residue 286 type sequence Q description binding site for Di-peptide GW9 B 501 and CYS B 285 source : AC3 14) chain B residue 287 type sequence F description binding site for Di-peptide GW9 B 501 and CYS B 285 source : AC3 15) chain B residue 288 type sequence R description binding site for Di-peptide GW9 B 501 and CYS B 285 source : AC3 16) chain B residue 289 type sequence S description binding site for Di-peptide GW9 B 501 and CYS B 285 source : AC3 17) chain B residue 323 type sequence H description binding site for Di-peptide GW9 B 501 and CYS B 285 source : AC3 18) chain B residue 326 type sequence I description binding site for Di-peptide GW9 B 501 and CYS B 285 source : AC3 19) chain B residue 327 type sequence Y description binding site for Di-peptide GW9 B 501 and CYS B 285 source : AC3 20) chain B residue 330 type sequence L description binding site for Di-peptide GW9 B 501 and CYS B 285 source : AC3 21) chain B residue 363 type sequence F description binding site for Di-peptide GW9 B 501 and CYS B 285 source : AC3 22) chain B residue 449 type sequence H description binding site for Di-peptide GW9 B 501 and CYS B 285 source : AC3 23) chain B residue 475 type sequence D description binding site for Di-peptide GW9 B 501 and CYS B 285 source : AC3 24) chain B residue 224 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2 25) chain B residue 286 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 26) chain B residue 323 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 27) chain B residue 449 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 28) chain B residue 473 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1

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