eF-site ID 6md1-A PDB Code 6md1 Chain A click to enlarge Title Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with GW9662 and Oleic acid Classification TRANSCRIPTION Compound Peroxisome proliferator-activated receptor gamma Source (PPARG_HUMAN) Sequence A:  ESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSP FVIYDMNSLMMGEDKIKEVAIRIFQGCQFRSVEAVQEITE YAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDG VLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALE LDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALE LQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKK TETDMSLHPLLQEIYKD Description Functional site 1) chain A residue 285 type sequence C description binding site for residue OLA A 501 source : AC1 2) chain A residue 287 type sequence F description binding site for residue OLA A 501 source : AC1 3) chain A residue 288 type sequence R description binding site for residue OLA A 501 source : AC1 4) chain A residue 341 type sequence I description binding site for residue OLA A 501 source : AC1 5) chain A residue 342 type sequence S description binding site for residue OLA A 501 source : AC1 6) chain A residue 343 type sequence E description binding site for residue OLA A 501 source : AC1 7) chain A residue 364 type sequence M description binding site for residue OLA A 501 source : AC1 8) chain A residue 286 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 9) chain A residue 323 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 10) chain A residue 449 type BINDING sequence H description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 11) chain A residue 473 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG source Swiss-Prot : SWS_FT_FI1 12) chain A residue 224 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2

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