eF-site ID 6k3j_13-A
PDB Code 6k3j
Model 13
Chain A

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Title Solution structure of APOBEC3G-CD2 with ssDNA, Product A
Classification HYDROLASE/DNA
Compound DNA dC->dU-editing enzyme APOBEC-3G
Source (6K3J)
Sequence A:  MDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLN
QRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQD
YRVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYD
DQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGC
PFQPWDGLDEHSQDLSGRLRAILQNQEN
Description


Functional site

1) chain A
residue 257
type
sequence H
description binding site for residue ZN A 401
source : AC1

2) chain A
residue 288
type
sequence C
description binding site for residue ZN A 401
source : AC1

3) chain A
residue 291
type
sequence C
description binding site for residue ZN A 401
source : AC1

4) chain A
residue 259
type ACT_SITE
sequence E
description Proton donor => ECO:0000255|PROSITE-ProRule:PRU01083
source Swiss-Prot : SWS_FT_FI1

5) chain A
residue 244
type SITE
sequence N
description Interaction with DNA => ECO:0000305
source Swiss-Prot : SWS_FT_FI3

6) chain A
residue 257
type BINDING
sequence H
description BINDING => ECO:0000269|PubMed:18288108, ECO:0000269|PubMed:18849968, ECO:0000269|PubMed:19153609
source Swiss-Prot : SWS_FT_FI2

7) chain A
residue 288
type BINDING
sequence C
description BINDING => ECO:0000269|PubMed:18288108, ECO:0000269|PubMed:18849968, ECO:0000269|PubMed:19153609
source Swiss-Prot : SWS_FT_FI2

8) chain A
residue 291
type BINDING
sequence C
description BINDING => ECO:0000269|PubMed:18288108, ECO:0000269|PubMed:18849968, ECO:0000269|PubMed:19153609
source Swiss-Prot : SWS_FT_FI2

9) chain A
residue 218
type MOD_RES
sequence T
description Phosphothreonine; by PKA and CAMK2 => ECO:0000269|PubMed:21659520
source Swiss-Prot : SWS_FT_FI4

10) chain A
residue 257-295
type prosite
sequence HAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEM
description CYT_DCMP_DEAMINASES_1 Cytidine and deoxycytidylate deaminases zinc-binding region signature. HAElcFLdvipfwkldldqdyrvtcftsws..........PCfs......CaqeM
source prosite : PS00903


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