eF-site ID 6k1e-A
PDB Code 6k1e
Chain A

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Title Crystal structure of EXD2 exonuclease domain soaked in Mg and GMP
Classification HYDROLASE
Compound Exonuclease 3'-5' domain-containing protein 2
Source (EXD2_HUMAN)
Sequence A:  AKVVTVSQEAEWDQIEPLLRSELEDFPVLGIDCEWVNLES
PLSLLQMASPSGLCVLVRLPKLICGGKTLPRTLLDILADG
TILKVGVGCSEDASKLLQDYGLVVRGCLDLRYLAMRQRNN
LLCNGLSLKSLAETVLNFPLLRCSNWDAETLTEDQVIYAA
RDAQISVALFLHLLGYSSWRKVLEKCQGVVDIPFRS
Description


Functional site

1) chain A
residue 108
type
sequence D
description binding site for residue MG A 301
source : AC1

2) chain A
residue 108
type
sequence D
description binding site for residue MG A 302
source : AC2

3) chain A
residue 110
type
sequence E
description binding site for residue MG A 302
source : AC2

4) chain A
residue 242
type
sequence Y
description binding site for residue MG B 301
source : AC3

5) chain A
residue 246
type
sequence D
description binding site for residue MG B 301
source : AC3

6) chain A
residue 108
type BINDING
sequence D
description BINDING => ECO:0000269|PubMed:31127291, ECO:0007744|PDB:6K19, ECO:0007744|PDB:6K1A, ECO:0007744|PDB:6K1B, ECO:0007744|PDB:6K1C, ECO:0007744|PDB:6K1D, ECO:0007744|PDB:6K1E
source Swiss-Prot : SWS_FT_FI1

7) chain A
residue 110
type BINDING
sequence E
description BINDING => ECO:0000269|PubMed:31127291, ECO:0007744|PDB:6K18, ECO:0007744|PDB:6K1A, ECO:0007744|PDB:6K1B, ECO:0007744|PDB:6K1D, ECO:0007744|PDB:6K1E
source Swiss-Prot : SWS_FT_FI2

8) chain A
residue 246
type BINDING
sequence D
description BINDING => ECO:0000269|PubMed:31127291, ECO:0007744|PDB:6K18, ECO:0007744|PDB:6K1A, ECO:0007744|PDB:6K1B, ECO:0007744|PDB:6K1D, ECO:0007744|PDB:6K1E
source Swiss-Prot : SWS_FT_FI2


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