|
|
eF-site ID
|
6k1d-B |
|
PDB Code
|
6k1d |
|
Chain
|
B |
|
click to enlarge
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Title
|
Crystal structure of EXD2 exonuclease domain soaked in Mn and GMP |
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Classification
|
HYDROLASE |
|
Compound
|
Exonuclease 3'-5' domain-containing protein 2 |
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Source
|
(EXD2_HUMAN) |
|
|
Sequence
|
B: |
AKVVTVSQEAEWDQIEPLLRSELEDFPVLGIDCEWVNASP
LSLLQMASPSGLCVLVRLPKLICGGKTLPRTLLDILADGT
ILKVGVGCSEDASKLLQDYGLVVRGCLDLRYLAMRQRNNL
LCNGLSLKSLAETVLNFPLLLRCSNWDAETLTEDQVIYAA
RDAQISVALFLHLLGYSWRKVLEKCQGVVDIPF
|
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
246 |
| type |
|
| sequence |
D
|
| description |
binding site for residue MN A 302
|
| source |
: AC2
|
|
|
2)
|
chain |
B |
| residue |
108 |
| type |
|
| sequence |
D
|
| description |
binding site for residue MN A 303
|
| source |
: AC3
|
|
|
3)
|
chain |
B |
| residue |
110 |
| type |
|
| sequence |
E
|
| description |
binding site for residue MN A 303
|
| source |
: AC3
|
|
|
4)
|
chain |
B |
| residue |
108 |
| type |
|
| sequence |
D
|
| description |
binding site for residue MN B 301
|
| source |
: AC4
|
|
|
5)
|
chain |
B |
| residue |
108 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:31127291, ECO:0007744|PDB:6K19, ECO:0007744|PDB:6K1A, ECO:0007744|PDB:6K1B, ECO:0007744|PDB:6K1C, ECO:0007744|PDB:6K1D, ECO:0007744|PDB:6K1E
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
B |
| residue |
110 |
| type |
BINDING |
| sequence |
E
|
| description |
BINDING => ECO:0000269|PubMed:31127291, ECO:0007744|PDB:6K18, ECO:0007744|PDB:6K1A, ECO:0007744|PDB:6K1B, ECO:0007744|PDB:6K1D, ECO:0007744|PDB:6K1E
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
7)
|
chain |
B |
| residue |
246 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:31127291, ECO:0007744|PDB:6K18, ECO:0007744|PDB:6K1A, ECO:0007744|PDB:6K1B, ECO:0007744|PDB:6K1D, ECO:0007744|PDB:6K1E
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|