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|
eF-site ID
|
6k1c-AB |
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PDB Code
|
6k1c |
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Chain
|
A, B |
|
click to enlarge
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Title
|
Crystal structure of EXD2 exonuclease domain soaked in Mg and dGMP |
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Classification
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HYDROLASE |
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Compound
|
Exonuclease 3'-5' domain-containing protein 2 |
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Source
|
(EXD2_HUMAN) |
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Sequence
|
A: |
AKVVTVSQEAEWDQIEPLLRSELEDFPVLGIDCEWVNASP
LSLLQMASPSGLCVLVRLPKLICGGKTLPRTLLDILADGT
ILKVGVGCSEDASKLLQDYGLVVRGCLDLRYLAMRQRNNL
LCNGLSLKSLAETVLNFPLLRCSNWDAETLTEDQVIYAAR
DAQISVALFLHLLGYSWRKVLEKCQGVVDIPFRS
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| B: |
AKVVTVSQEAEWDQIEPLLRSELEDFPVLGIDCEWVNASP
LSLLQMASPSGLCVLVRLPKLICGGKTLPRTLLDILADGT
ILKVGVGCSEDASKLLQDYGLVVRGCLDLRYLAMRQRNNL
LCNGLSLKSLAETVLNFPLLRCSNWDAETLTEDQVIYAAR
DAQISVALFLHLLGYSWRKVLEKCQGVVDIPFR
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Description
|
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Functional site
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|
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1)
|
chain |
A |
| residue |
108 |
| type |
|
| sequence |
D
|
| description |
binding site for residue MG A 301
|
| source |
: AC1
|
|
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2)
|
chain |
B |
| residue |
108 |
| type |
|
| sequence |
D
|
| description |
binding site for residue MG B 301
|
| source |
: AC2
|
|
|
3)
|
chain |
A |
| residue |
108 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:31127291, ECO:0007744|PDB:6K19, ECO:0007744|PDB:6K1A, ECO:0007744|PDB:6K1B, ECO:0007744|PDB:6K1C, ECO:0007744|PDB:6K1D, ECO:0007744|PDB:6K1E
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
B |
| residue |
108 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:31127291, ECO:0007744|PDB:6K19, ECO:0007744|PDB:6K1A, ECO:0007744|PDB:6K1B, ECO:0007744|PDB:6K1C, ECO:0007744|PDB:6K1D, ECO:0007744|PDB:6K1E
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
A |
| residue |
110 |
| type |
BINDING |
| sequence |
E
|
| description |
BINDING => ECO:0000269|PubMed:31127291, ECO:0007744|PDB:6K18, ECO:0007744|PDB:6K1A, ECO:0007744|PDB:6K1B, ECO:0007744|PDB:6K1D, ECO:0007744|PDB:6K1E
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
6)
|
chain |
A |
| residue |
246 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:31127291, ECO:0007744|PDB:6K18, ECO:0007744|PDB:6K1A, ECO:0007744|PDB:6K1B, ECO:0007744|PDB:6K1D, ECO:0007744|PDB:6K1E
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
7)
|
chain |
B |
| residue |
110 |
| type |
BINDING |
| sequence |
E
|
| description |
BINDING => ECO:0000269|PubMed:31127291, ECO:0007744|PDB:6K18, ECO:0007744|PDB:6K1A, ECO:0007744|PDB:6K1B, ECO:0007744|PDB:6K1D, ECO:0007744|PDB:6K1E
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
8)
|
chain |
B |
| residue |
246 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:31127291, ECO:0007744|PDB:6K18, ECO:0007744|PDB:6K1A, ECO:0007744|PDB:6K1B, ECO:0007744|PDB:6K1D, ECO:0007744|PDB:6K1E
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|