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eF-site ID
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6j6n-C |
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PDB Code
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6j6n |
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Chain
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C |
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click to enlarge
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Title
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Cryo-EM structure of the yeast B*-b1 complex at an average resolution of 3.86 angstrom |
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Classification
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SPLICING |
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Compound
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Pre-mRNA-splicing factor 8 |
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Source
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ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae S288c; |
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Sequence
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C: |
EHPYGKEVEVLMETKNTQSPQTPLVEPVTERTKLQEHTIF
TQLKKNIPKTRYNRDYMLSMANIPERIINVGVIGPLHSGK
TSLMDLLVIDSHKRIPDMSKNVELGWKPLRYLDNLKQEID
RGLSIKLNGSTLLCTDLESKSRMINFLDAPGHVNFMDETA
VALAASDLVLIVIDVVEGVTFVVEQLIKQSIKNNVAMCFV
INKLDRLILDLKLPPMDAYLKLNHIIANINSFTKGNVFSP
IDNNIIFASTKLGFTFTIKEFVSYYYAHSIPSSKIDDFTT
RLWGSVYYHKGNFRTKPFENVEKYPTFVEFILIPLYKIFS
YALSMEKDKLKNLLRSNFRVNLSQEALQYDPQPFLKHVLQ
LIFRQQTGLVDAITRCYQPFELFDNKTAHLSIPGKSTPEG
TLWAHVLKTVDYGGAEWSLVRIYSGLLKRGDTVRILDTSQ
SESRQKRQLHDEDDETPSCEVEEIGLLGGRYVYPVHEAHK
GQIVLIKGISSAYIKSATLYSVKSKEDMKQLKFFKPLDYI
TEAVFKIVLQPLLPRELPKLLDALNKISKYYPGVIIKVEE
SGEHVILGNGELYMDCLLYDLRASYAKIEIKISDPLTVFS
ESCSNESSRLGEENLPGLSISVAAEPMDSKMIQDLSRNTL
GKGQNCLDIDGIMDNPRKLSKILRTEYGWDSLASRNVWSF
YNGNVLINDTLPDEISPELLSKYKEQIIQGFYWAVKEGPL
AEEPIYGVQYKLLSISVPSDVNIDVMKSQIIPLMKKACYV
GLLTAIPILLEPIYEVDITVHAPLLPIVEELMKKRRGSRI
YKTIKVAGTPLLEVRGQVPVIESAGFETDLRLSTNGLGMC
QLYFWHKIWRKVPGDVLDKDAFIPKLKPAPINSLSRDFVM
KTRRRKGISTGGFMSNDGPTLEKYISAELYAQLRENGLVP
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Description
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(1) |
Pre-mRNA-splicing factor 8, Pre-mRNA-splicing factor SNU114, Pre-mRNA-splicing factor CWC21, Pre-mRNA-splicing factor PRP46, Pre-mRNA-processing protein 45, Pre-mRNA-splicing factor SLT11, Pre-mRNA-splicing factor CWC2, Pre-mRNA-splicing factor CWC15, Pre-mRNA-splicing factor BUD31, Pre-mRNA-splicing factor CWC22, Pre-mRNA-splicing factor CEF1, Pre-mRNA-splicing factor CLF1, Pre-mRNA-splicing factor SYF2, Pre-mRNA-processing factor 17, Pre-mRNA-splicing factor ISY1, Pre-mRNA-splicing factor SYF1, U2 small nuclear ribonucleoprotein B'', U2 small nuclear ribonucleoprotein A', Pre-mRNA-splicing factor SNT309, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein G, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein-associated protein B, Small nuclear ribonucleoprotein Sm D3, Pre-mRNA-processing factor 19/RNA Complex
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Functional site
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|
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1)
|
chain |
C |
| residue |
141 |
| type |
|
| sequence |
P
|
| description |
binding site for residue GTP C 1500
|
| source |
: AC2
|
|
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2)
|
chain |
C |
| residue |
142 |
| type |
|
| sequence |
L
|
| description |
binding site for residue GTP C 1500
|
| source |
: AC2
|
|
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3)
|
chain |
C |
| residue |
143 |
| type |
|
| sequence |
H
|
| description |
binding site for residue GTP C 1500
|
| source |
: AC2
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|
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4)
|
chain |
C |
| residue |
144 |
| type |
|
| sequence |
S
|
| description |
binding site for residue GTP C 1500
|
| source |
: AC2
|
|
|
5)
|
chain |
C |
| residue |
145 |
| type |
|
| sequence |
G
|
| description |
binding site for residue GTP C 1500
|
| source |
: AC2
|
|
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6)
|
chain |
C |
| residue |
146 |
| type |
|
| sequence |
K
|
| description |
binding site for residue GTP C 1500
|
| source |
: AC2
|
|
|
7)
|
chain |
C |
| residue |
147 |
| type |
|
| sequence |
T
|
| description |
binding site for residue GTP C 1500
|
| source |
: AC2
|
|
|
8)
|
chain |
C |
| residue |
148 |
| type |
|
| sequence |
S
|
| description |
binding site for residue GTP C 1500
|
| source |
: AC2
|
|
|
9)
|
chain |
C |
| residue |
176 |
| type |
|
| sequence |
R
|
| description |
binding site for residue GTP C 1500
|
| source |
: AC2
|
|
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10)
|
chain |
C |
| residue |
189 |
| type |
|
| sequence |
L
|
| description |
binding site for residue GTP C 1500
|
| source |
: AC2
|
|
|
11)
|
chain |
C |
| residue |
190 |
| type |
|
| sequence |
S
|
| description |
binding site for residue GTP C 1500
|
| source |
: AC2
|
|
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12)
|
chain |
C |
| residue |
216 |
| type |
|
| sequence |
P
|
| description |
binding site for residue GTP C 1500
|
| source |
: AC2
|
|
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13)
|
chain |
C |
| residue |
217 |
| type |
|
| sequence |
G
|
| description |
binding site for residue GTP C 1500
|
| source |
: AC2
|
|
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14)
|
chain |
C |
| residue |
269 |
| type |
|
| sequence |
K
|
| description |
binding site for residue GTP C 1500
|
| source |
: AC2
|
|
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15)
|
chain |
C |
| residue |
271 |
| type |
|
| sequence |
D
|
| description |
binding site for residue GTP C 1500
|
| source |
: AC2
|
|
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16)
|
chain |
C |
| residue |
315 |
| type |
|
| sequence |
S
|
| description |
binding site for residue GTP C 1500
|
| source |
: AC2
|
|
|
17)
|
chain |
C |
| residue |
316 |
| type |
|
| sequence |
T
|
| description |
binding site for residue GTP C 1500
|
| source |
: AC2
|
|
|
18)
|
chain |
C |
| residue |
317 |
| type |
|
| sequence |
K
|
| description |
binding site for residue GTP C 1500
|
| source |
: AC2
|
|
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19)
|
chain |
C |
| residue |
147 |
| type |
|
| sequence |
T
|
| description |
binding site for residue MG C 1501
|
| source |
: AC3
|
|
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20)
|
chain |
C |
| residue |
190 |
| type |
|
| sequence |
S
|
| description |
binding site for residue MG C 1501
|
| source |
: AC3
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|
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21)
|
chain |
C |
| residue |
268 |
| type |
MOD_RES |
| sequence |
N
|
| description |
Phosphoserine => ECO:0007744|PubMed:18407956
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| source |
Swiss-Prot : SWS_FT_FI1
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22)
|
chain |
C |
| residue |
88 |
| type |
MOD_RES |
| sequence |
T
|
| description |
Phosphothreonine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198
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| source |
Swiss-Prot : SWS_FT_FI3
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