eF-site ID 6iqw-ABCDEFI PDB Code 6iqw Chain A, B, C, D, E, F, I click to enlarge Title Cryo-EM structure of Csm effector complex Classification RNA BINDING PROTEIN/RNA Compound Csm1 Source (6IQW) Sequence A:  MEIDELTALGGLLHDIGKPVQRAGLYSGDHSTQGARFLRD LAENTGRAEYELLSLFSEFHHKGHMKNDELMIRRIKELSP ERFGLTMEDVLNALWIVYEADNLASGPQASRPLYSVFNPG KAYPWAELDFEKELPVPGDVFSIRSQDYRELVKRLWEELS KAKLRSDRLLPVLEKYLTFVSSVTSEGNIISLYDHMRMTS AIALAMLRAGCTAEDVRSGRCRKEKRFLLIEGDFSGIQDF IYRVSGKGTLKYLRARSAYLELIGWDVVLEILSRLGLTRA NVVFNAGGHFMIIAQNTPDAVKELEEIRAKAVEWLYREFE SDLYLAIEWEPVSGREFGREGGKNLFAEARKRLKHKLTVR KLKRFGEIKGLFEHGHTERLAECPVCGRELPEGKLEPSAS DPETKVCPTCNRLVSLGGNLPKLLGFGRTAKNDAGVLVEG PFSGFVPYLQGGRPVGEQILVKNTLNPGEIPESAQFVPYF VADYFKKDPKGGVATFEELSMASTGTRRLGVMKGDVDRLG EFFSSMDSPSKLATASRFMDYFFKGYIGAIIEGKFGYIIG DVPSLRDWPEEPDIVVVYAGGDDFFIVGAWDQIFELAFRV RRAFNAYTGGKLTLSVGLGYFDERTPIYRMADVVSERLDT AKDEGRNRVFVVGRSRPLDGKHKLSYEWNHYEELWRTYAP RIYAGNGRLKGKLESKKGLLWKLLEIRELYVRDPNDVRWA YLTAYLLGRHGLSDLFPELVGIDTKAVERKEPQPVYWVDG VLKIVLMAVRR B:  QWEAIQPYFDNVVREAKNFLEWSPNKRLANAVTVAAYLTS QGLKTNQVRKILDMARTTELKVKRGEGDIKDDLVKMRYLL AYTVGKATGQSKYSLDAFHRILDPMLEVLMGSPKKENFEK FYDFLQAVVAYHKF C:  RFYGKIVIKGKIKAVTGLHIGSNPVIKDPHTGLPYIPGSS LKGRLRSLFEILVNSRLGEWREKYPSLANYSPGSCRPDNQ ENCGKFFNRKINRGWIHVCPDYETALACPVCRLFGASGKE SNFPSRIIVRDAFLTKEWEEKWRAGEAITEAKIEVGIDRV TSQANPRTNERVVAGAEFEFEIIYNVENTTHWRDDIKNLL TAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTG KDEDIVSIDAREKSVSDILSGFDSLFSEVEGKLE D:  MDRRFYGKIVIKGKIKAVTGLHIGSQPVIKDPHTGLPYIP GSSLKGRLRSLFEILVNSRLGEWREKYPSLANYSPGSCRP DNQENCGKFFNRKINRGWIHVCPDYETALACPVCRLFGAS GKESNFPSRIIVRDAFLTKEWEEKWRAGEAITEAKIEVGI DRVTSQANPRTNERVVAGAEFEFEIIYNVENTTHWRDDIK NLLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYY RTGKDEDIVSIDAREKSVSDILSGFDSLFSE E:  PKFIAVKLIPKGPFRDIPRADTLFGAIGNAISAIHGQSAV EELVDAFVGGARISSAFPYSGDTYYLPKPLSVEPALEGIL TGLDEEERYTTAKRLRKAKYLDLKNFELALRLRPFTIPEE IPYARVDVPRVVLDRVTQDSSIYFWEEIRFREKSGVYFLY SGPREVFDGYIAPAMRFLGWGAGLFEVEFHEMKIDAPGSE YSVTLSNALPTKTPVLWRLLRKGGWSFGRRKPRMTFIAEG SIVKNDPGGMERLELGLSHEVYVYGLTFPLGVELPEG F:  TERTLKVLSPLHIGTGNELTPVDIYPRENIIHVLDTERLV NDLMNLGVELNEILALLKNPPGDAYIWKGYIEEFHLDPSD YSIYTLKIHGSMQIKEFIKLNGRPYIPGSSLKGAIRTAVL YKALKECGDARAVMRVVSKVNGDVARDIGRSEDVLDYYMS FLSRARIDRKRADDLLEAIVFGMEPDRRSKIRYEPKRDPM KALIVRDSKPVGRKHLAVYHVEVIGNPQPIPIWVEAIEPG AATDVEIHVDTEALRLNADYFNGLLWECLKERGEPGEVFE DFLWEAVDEFYTAVMKYETIEVQKFGRYTSQVRSFYASLE DHSGHVLRLGKTRRLADGMPMGWVVL I:  GUGGAAAGUGGCCCGAAACCCUUC Description (1)  Csm1, Csm2, Csm3, Csm4, Csm5/RNA Complex Functional site 1) chain A residue 290 type sequence F description binding site for residue ATP A 801 source : AC1 2) chain A residue 295 type sequence H description binding site for residue ATP A 801 source : AC1 3) chain A residue 521 type sequence D description binding site for residue ATP A 801 source : AC1 4) chain A residue 522 type sequence V description binding site for residue ATP A 801 source : AC1 5) chain A residue 524 type sequence R description binding site for residue ATP A 801 source : AC1 6) chain A residue 525 type sequence L description binding site for residue ATP A 801 source : AC1 7) chain A residue 526 type sequence G description binding site for residue ATP A 801 source : AC1 8) chain A residue 529 type sequence F description binding site for residue ATP A 801 source : AC1 9) chain A residue 542 type sequence S description binding site for residue ATP A 801 source : AC1 10) chain A residue 587 type sequence G description binding site for residue ATP A 801 source : AC1 11) chain A residue 588 type sequence D description binding site for residue ATP A 801 source : AC1 12) chain A residue 648 type sequence K description binding site for residue ATP A 801 source : AC1 13) chain A residue 652 type sequence R description binding site for residue ATP A 801 source : AC1 14) chain E residue 93 type sequence A description binding site for residue ATP A 801 source : AC1

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