eF-site ID 6ipm-A PDB Code 6ipm Chain A click to enlarge Title Binary Complex of Human DNA Polymerase Mu with MgdCTP Classification TRANSFERASE Compound DNA-directed DNA/RNA polymerase mu Source (DPOLM_HUMAN) Sequence A:  WMPAYACQRPTPLTHHNTGLSEALEILAEAAGFEGSEGRL LTFCRAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQEL LEHGVCEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYR EGLRTLDDLREQPQKLTQQQKAGLQHHQDLSTPVLRSDVD ALQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLIT HPKEGQEAGLLPRVMCRLQDQGLILYHQHQHSAFERSFCI FRLPQPGSWKAVRVDLVVAPVSQFPFALLGWTGSKLFQRE LRRFSRKEKGLWLNSHGLFDPEQKTFFQAASEEDIFRHLG LEYLPPEQRNA Description Functional site 1) chain A residue 319 type sequence G description binding site for residue DCP A 501 source : AC1 2) chain A residue 320 type sequence G description binding site for residue DCP A 501 source : AC1 3) chain A residue 323 type sequence R description binding site for residue DCP A 501 source : AC1 4) chain A residue 325 type sequence K description binding site for residue DCP A 501 source : AC1 5) chain A residue 328 type sequence G description binding site for residue DCP A 501 source : AC1 6) chain A residue 329 type sequence H description binding site for residue DCP A 501 source : AC1 7) chain A residue 330 type sequence D description binding site for residue DCP A 501 source : AC1 8) chain A residue 332 type sequence D description binding site for residue DCP A 501 source : AC1 9) chain A residue 433 type sequence G description binding site for residue DCP A 501 source : AC1 10) chain A residue 434 type sequence W description binding site for residue DCP A 501 source : AC1 11) chain A residue 435 type sequence T description binding site for residue DCP A 501 source : AC1 12) chain A residue 436 type sequence G description binding site for residue DCP A 501 source : AC1 13) chain A residue 437 type sequence S description binding site for residue DCP A 501 source : AC1 14) chain A residue 438 type sequence K description binding site for residue DCP A 501 source : AC1 15) chain A residue 330 type sequence D description binding site for residue MG A 502 source : AC2 16) chain A residue 332 type sequence D description binding site for residue MG A 502 source : AC2 17) chain A residue 322 type sequence R description binding site for residue SO4 A 503 source : AC3 18) chain A residue 489 type sequence P description binding site for residue SO4 A 503 source : AC3 19) chain A residue 247 type sequence G description binding site for residue SO4 A 504 source : AC4 20) chain A residue 249 type sequence K description binding site for residue SO4 A 504 source : AC4 21) chain A residue 250 type sequence T description binding site for residue SO4 A 504 source : AC4 22) chain A residue 172 type sequence S description binding site for residue SO4 A 505 source : AC5 23) chain A residue 173 type sequence E description binding site for residue SO4 A 505 source : AC5 24) chain A residue 174 type sequence G description binding site for residue SO4 A 505 source : AC5 25) chain A residue 175 type sequence R description binding site for residue SO4 A 505 source : AC5 26) chain A residue 229 type sequence R description binding site for residue SO4 A 506 source : AC6 27) chain A residue 253 type sequence R description binding site for residue SO4 A 507 source : AC7 28) chain A residue 256 type sequence R description binding site for residue SO4 A 507 source : AC7 29) chain A residue 445 type sequence R description binding site for residue SO4 A 508 source : AC8 30) chain A residue 457 type sequence N description binding site for residue SO4 A 508 source : AC8 31) chain A residue 458 type sequence S description binding site for residue SO4 A 508 source : AC8 32) chain A residue 459 type sequence H description binding site for residue SO4 A 508 source : AC8 33) chain A residue 329 type sequence H description binding site for residue SO4 A 509 source : AC9 34) chain A residue 416 type sequence R description binding site for residue SO4 A 509 source : AC9 35) chain A residue 319-338 type prosite sequence GGFRRGKLQGHDVDFLITHP description DNA_POLYMERASE_X DNA polymerase family X signature. GGFrRGklqGhDVDFLIthP source prosite : PS00522 36) chain A residue 433 type SITE sequence G description Responsible for the low discrimination between dNTP and rNTP source Swiss-Prot : SWS_FT_FI2 37) chain A residue 330 type BINDING sequence D description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 38) chain A residue 332 type BINDING sequence D description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 39) chain A residue 418 type BINDING sequence D description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1

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