eF-site ID 6ipd-A PDB Code 6ipd Chain A click to enlarge Title Post-catalytic Complex of Human DNA Polymerase Mu with Templating Adenine and Mn-8oxodGMP Classification TRANSFERASE/DNA Compound DNA-directed DNA/RNA polymerase mu Source (6IPD) Sequence A:  MPAYACQRPTPLTHHNTGLSEALEILAEAAGFEGSEGRLL TFCRAASVLKALPSPVTTLSQLQGLPHFGEHSSRVVQELL EHGVCEEVERVRRSERYQTMKLFTQIFGVGVKTADRWYRE GLRTLDDLREQPQKLTQQQKAGLQHHQDLSTPVLRSDVDA LQQVVEEAVGQALPGATVTLTGGFRRGKLQGHDVDFLITH PKEGQEAGLLPRVMCRLQDQGLILYHQHFERSFCIFRLPQ PGSWKAVRVDLVVAPVSQFPFALLGWTGSKLFQRELRRFS RKEKGLWLNSHGLFDPEQKTFFQAASEEDIFRHLGLEYLP PEQRNA Description Functional site 1) chain A residue 330 type sequence D description binding site for residue MN A 501 source : AC1 2) chain A residue 332 type sequence D description binding site for residue MN A 501 source : AC1 3) chain A residue 330 type sequence D description binding site for residue MN A 502 source : AC2 4) chain A residue 332 type sequence D description binding site for residue MN A 502 source : AC2 5) chain A residue 418 type sequence D description binding site for residue MN A 502 source : AC2 6) chain A residue 241 type sequence T description binding site for residue NA A 503 source : AC3 7) chain A residue 243 type sequence I description binding site for residue NA A 503 source : AC3 8) chain A residue 246 type sequence V description binding site for residue NA A 503 source : AC3 9) chain A residue 386 type sequence E description binding site for residue NA A 504 source : AC4 10) chain A residue 459 type sequence H description binding site for residue NA A 504 source : AC4 11) chain A residue 319 type sequence G description binding site for residue OXD A 505 source : AC5 12) chain A residue 320 type sequence G description binding site for residue OXD A 505 source : AC5 13) chain A residue 323 type sequence R description binding site for residue OXD A 505 source : AC5 14) chain A residue 330 type sequence D description binding site for residue OXD A 505 source : AC5 15) chain A residue 332 type sequence D description binding site for residue OXD A 505 source : AC5 16) chain A residue 325 type sequence K description binding site for residue EPE A 506 source : AC6 17) chain A residue 326 type sequence L description binding site for residue EPE A 506 source : AC6 18) chain A residue 327 type sequence Q description binding site for residue EPE A 506 source : AC6 19) chain A residue 485 type sequence E description binding site for residue EPE A 506 source : AC6 20) chain A residue 190 type sequence P description binding site for residue EDO A 507 source : AC7 21) chain A residue 191 type sequence S description binding site for residue EDO A 507 source : AC7 22) chain A residue 192 type sequence P description binding site for residue EDO A 507 source : AC7 23) chain A residue 198 type sequence Q description binding site for residue EDO A 507 source : AC7 24) chain A residue 438 type sequence K description binding site for residue EDO A 508 source : AC8 25) chain A residue 442 type sequence R description binding site for residue EDO A 508 source : AC8 26) chain A residue 387 type sequence R description binding site for residue EDO A 509 source : AC9 27) chain A residue 433 type sequence G description binding site for residue EDO A 509 source : AC9 28) chain A residue 434 type sequence W description binding site for residue EDO A 509 source : AC9 29) chain A residue 445 type sequence R description binding site for residue EDO A 509 source : AC9 30) chain A residue 330 type BINDING sequence D description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 31) chain A residue 332 type BINDING sequence D description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 32) chain A residue 418 type BINDING sequence D description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 33) chain A residue 433 type SITE sequence G description Responsible for the low discrimination between dNTP and rNTP source Swiss-Prot : SWS_FT_FI2 34) chain A residue 319-338 type prosite sequence GGFRRGKLQGHDVDFLITHP description DNA_POLYMERASE_X DNA polymerase family X signature. GGFrRGklqGhDVDFLIthP source prosite : PS00522

Display surface Download Links