|
eF-site ID
|
6ilm-A |
PDB Code
|
6ilm |
Chain
|
A |
|
click to enlarge
|
|
Title
|
Cryo-EM structure of Echovirus 6 complexed with its uncoating receptor FcRn at PH 7.4 |
Classification
|
VIRUS |
Compound
|
Capsid protein VP1 |
Source
|
ORGANISM_SCIENTIFIC: Echovirus E6; |
|
Sequence
|
A: |
NDVQNAIDRAVVRVADTMPSGPSNSESIPALTAAETGHTS
QVVPSDTIQTRHVRNFHVRSESSVENFLSRSACVYIVEYK
TRDDTPDKMYDSWVINTRQVAQLRRKLEFFTYVRFDVEVT
FVITSVQDDSTRQNTDTPALTHQIMYVPPGGPIPQAVDDY
NWQTSTNPSVFWTEGNAPPRMSIPFMSVGNAYSNFYDGWS
HFSQTGVYGFNTLNNMGKLYFRHVNDKTISPITSKVRIYF
KPKHVKAWVPRPPRLCEYTHKDNVDFEPKGVTTSRTQLTI
SNSTHVENY
|
|
Description
|
(1) |
Capsid protein VP1 (E.C.3.4.22.29,3.6.1.15,3.4.22.28,2.7.7.48), Capsid protein VP2 (E.C.3.4.22.29,3.6.1.15,3.4.22.28,2.7.7.48), Capsid protein VP3 (E.C.3.4.22.29,3.6.1.15,3.4.22.28,2.7.7.48), Capsid protein VP4 (E.C.3.4.22.29,3.6.1.15,3.4.22.28,2.7.7.48), FcRn heavy chain, FcRn light chain
|
|
Functional site
|
|
1)
|
chain |
A |
residue |
97 |
type |
|
sequence |
T
|
description |
binding site for residue SPH A 301
|
source |
: AC1
|
|
2)
|
chain |
A |
residue |
115 |
type |
|
sequence |
F
|
description |
binding site for residue SPH A 301
|
source |
: AC1
|
|
3)
|
chain |
A |
residue |
146 |
type |
|
sequence |
Y
|
description |
binding site for residue SPH A 301
|
source |
: AC1
|
|
4)
|
chain |
A |
residue |
183 |
type |
|
sequence |
I
|
description |
binding site for residue SPH A 301
|
source |
: AC1
|
|
5)
|
chain |
A |
residue |
192 |
type |
|
sequence |
Y
|
description |
binding site for residue SPH A 301
|
source |
: AC1
|
|
6)
|
chain |
A |
residue |
194 |
type |
|
sequence |
N
|
description |
binding site for residue SPH A 301
|
source |
: AC1
|
|
7)
|
chain |
A |
residue |
216 |
type |
|
sequence |
M
|
description |
binding site for residue SPH A 301
|
source |
: AC1
|
|
8)
|
chain |
A |
residue |
219 |
type |
|
sequence |
L
|
description |
binding site for residue SPH A 301
|
source |
: AC1
|
|
9)
|
chain |
A |
residue |
14 |
type |
|
sequence |
V
|
description |
binding site for residue K A 302
|
source |
: AC2
|
|
10)
|
chain |
A |
residue |
16 |
type |
|
sequence |
D
|
description |
binding site for residue K A 302
|
source |
: AC2
|
|
11)
|
chain |
A |
residue |
55 |
type |
|
sequence |
N
|
description |
binding site for residue K A 302
|
source |
: AC2
|
|
12)
|
chain |
A |
residue |
31 |
type |
|
sequence |
L
|
description |
binding site for residue NA D 101
|
source |
: AC3
|
|
|
|