eF-site ID 6iis-ABEF
PDB Code 6iis
Chain A, B, E, F

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Title Complex structure of the HRP3 PWWP domain with both a 16-bp TA-rich DNA and an H3K36me3-containing histone peptide
Classification DNA BINDING PROTEIN/DNA
Compound Hepatoma-derived growth factor-related protein 3
Source (6IIS)
Sequence A:  MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPP
ANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKG
FNEGLWEIENNPGVKFTGY
B:  MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPP
ANKYPIFFFGTHETAFLGPKDLFPYKEYKDKFGKSNKRKG
FNEGLWEIENNPGVKFTGY
E:  GGVXK
F:  GGVXK
Description


Functional site

1) chain E
residue 36
type MOD_RES
sequence X
description N6-methyllysine; alternate => ECO:0000269|PubMed:15983376, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16627869, ECO:0000269|PubMed:17194708
source Swiss-Prot : SWS_FT_FI1

2) chain F
residue 36
type MOD_RES
sequence X
description N6-methyllysine; alternate => ECO:0000269|PubMed:15983376, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16627869, ECO:0000269|PubMed:17194708
source Swiss-Prot : SWS_FT_FI1

3) chain E
residue 37
type MOD_RES
sequence K
description N6-methyllysine => ECO:0000269|PubMed:15983376
source Swiss-Prot : SWS_FT_FI2

4) chain F
residue 37
type MOD_RES
sequence K
description N6-methyllysine => ECO:0000269|PubMed:15983376
source Swiss-Prot : SWS_FT_FI2


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