eF-site ID 6ieq-BDEGHL PDB Code 6ieq Chain B, D, E, G, H, L click to enlarge Title Crystal Structure of HIV-1 Env ConM SOSIP.v7 in Complex with bNAb PGT124 and 35O22 Classification VIRAL PROTEIN Compound Envelope glycoprotein gp160 Source (6IEQ) Sequence B:  GFLGAAGSTMGAASMTLTVQARNLLSGIVQQQLQLTVWGI KQLQARVLAVERYLKDQQLLGIWGCSGKLICCTNVPWNSS WSNKSQDEIWDNMTWMEWDKEINNYTDIIYSLIEESQNQQ EKNEQELLALD D:  EGQLVQSGAELKKPGASVKISCKTSGYRFNFYHINWIRQT AGRGPEWMGWISPYSGDKNLAPAFQDRVIMTTDTEVPVTS FTSTGAAYMEIRNLKFDDTGTYFCAKGLLRDGSSTWLPYL WGQGTLLTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLV KDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVV TVPSSSLGTQTYICNVNHKPSNTKVDKRV E:  SVLTQSASVSGSLGQSVTISCTGPNSVCCSHKSISWYQWP PGRAPTLIIYEDNERAPGISPRFSGYKSYWSAYLTISDLR PEDETTYYCCSYTHNSGCVFGTGTKVSVLGQSKANPSVTL FPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKA GVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTH EGSTVEKTVAPTE G:  ENLWVTVYYGVPVWKDAETTLFCASDAKAYDTEKRNVWAT HCCVPTDPNPQEIVLENVTENFNMWKNNMVEQMHTDIISL WDQSLKPCVKLTPLCVTLNCTDVNATNNTEEIKNCSFNIT TELRDKKKKVYALFYKLDVVPIDDNNSYRLINCNTSAITQ ACPKVSFEPIPIHYCAPAGFAILKCNDKKFNGTGPCKNVS TVQCTHGIKPVVSTQLLLNGSLAEEEIIIRSENITNNAKT IIVQLNESVEINCTRPNNNTRKSIRIGPGQWFYATGDIIG DIRQAHCNISRTKWNKTLQQVAKKLREHFNKTIIFNPSSG GDLEITTHSFNCGGEFFYCNTSELFNSNNTITLPCRIKQI INMWQRVGQAMYAPPIEGKIRCTSNITGLLLTRDGNNNTE TFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTRCKRRV H:  QVQLQESGPGLVRPSETLSVTCIVSGGSISNYYWTWIRQS PGKGLEWIGYISDRETTTYNPSLNSRAVISRDTSKNQLSL QLRSVTTADTAIYFCATARRGQRIYGVVSFGEFFYYYYMD VWGKGTAVTVSSASTKGPSVFPLAPSSSTSGGTAALGCLV KDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVV TVPSSSLGTQTYICNVNHKPSNTKVDKKVEP L:  YVSPLSVALGETARISCGRQALGSRAVQWYQHKPGQAPIL LIYNNQDRPSGIPERFSGTPDINFGTTATLTISGVEVGDE ADYYCHMWDSRSGFSWSFGGATRLTVLSQPKAAPSVTLFP PSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGV ETTTPSKQSNNKYAASSYLSLTPEQWKSHKSYSCQVTHEG STVEKTVAPT Description Functional site 1) chain L residue 192-198 type prosite sequence YSCQVTH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH source prosite : PS00290 2) chain D residue 194-200 type prosite sequence YICNVNH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH source prosite : PS00290 3) chain H residue 192-198 type prosite sequence YICNVNH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH source prosite : PS00290 4) chain E residue 195-201 type prosite sequence YSCQVTH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH source prosite : PS00290

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