eF-site ID 6i04-ABCDHL PDB Code 6i04 Chain A, B, C, D, H, L click to enlarge Title Crystal structure of Sema domain of the Met receptor in complex with FAB Classification IMMUNE SYSTEM Compound Hepatocyte growth factor receptor Source (6I04) Sequence A:  YQLPNFTAETPIQNVILHEHHIFLGATNYIYVLNEEDLQK VAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMAL VVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHC IFSPQIEEPSQCPDCVVSALGAKVLSSVKDRFINFFVGNT INSSYFPLHSISVRRLKETKDGFMFLTDQSYIDVLPEFRD SYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCS INSGLHSYMEMPLECILTKEVFNILQAAYVSKPGAQLARQ IGASLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVND FFNKINVRCLQHFYGPNCEEYRTEFTTALQRVDLFMGQFS EVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTP HVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPL NG B:  YQLPNFTAETPIQNVILHEHHIFLGATNYIYVLNEEDLQK VAEYKTGPVLEHPDCFPCQDCSVWKDNINMALVVDTYYDD QLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEE PSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSPLHS ISVRRLKETKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAF ESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYME MPLECILTKEVFNILQAAYVSKPGAQLARQIGASLNDDIL FGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKINVRCL QHFYGPNCEEYRTEFTTALQRVDLFMGQFSEVLLTSISTF IKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFLLDSHP VSPEVIVEHTLNQNGYTLVITGKKITKIPLNG C:  QLQLQESGPGLVKPSETLSLTCTVSGGSISSSVYYWSWIR QPPGKGLEWIGVIYPSGNTYYSPSLKSRVTISVDTSKNQF SLKLSSVTAADTAVYYCARTIYDLFDIWGQGTMVTVSSAS TKGPSVFPLAPSSKTAALGCLVKDYFPEPVTVSWNSGALT SGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNH KPSNTKVDKKVEPK D:  DIQMTQSPSSVSASVGDRVTITCRASQGISSWLAWYQQKP GKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQP EDFATYYCLQANSFPPTFGGGTKVEIKRTVAAPSVFIFPP SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQG LSSPVTKSFNRG H:  QLQLQESGPGLVKPSETLSLTCTVSGGSISSSVYYWSWIR QPPGKGLEWIGVIYPSGNTYYSPSLKSRVTISVDTSKNQF SLKLSSVTAADTAVYYCARTIYDLFDIWGQGTMVTVSSAS TKGPSVFPLAPTAALGCLVKDYFPEPVTVSWNSGALTSGV HTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPS NTKVDKKVEPK L:  DIQMTQSPSSVSASVGDRVTITCRASQGISSWLAWYQQKP GKAPKLLIYAASSLQSGVPSRFSGSGSGTDFTLTISSLQP EDFATYYCLQANSFPPTFGGGTKVEIKRTVAAPSVFIFPP SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQG LSSPVTKSFNRG Description Functional site 1) chain L residue 192-198 type prosite sequence YACEVTH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH source prosite : PS00290 2) chain H residue 199-205 type prosite sequence YICNVNH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH source prosite : PS00290 3) chain A residue 45 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 4) chain A residue 149 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 5) chain A residue 202 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 6) chain B residue 45 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 7) chain B residue 149 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 8) chain B residue 202 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 9) chain A residue 106 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19196183 source Swiss-Prot : SWS_FT_FI3

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