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eF-site ID
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6hwd-a |
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PDB Code
|
6hwd |
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Chain
|
a |
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click to enlarge
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Title
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Yeast 20S proteasome beta2-G45A mutant in complex with bortezomib |
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Classification
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HYDROLASE |
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Compound
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Proteasome subunit alpha type-2 |
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Source
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ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae S288c; |
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Sequence
|
a: |
TQQPIVTGTSVISMKYDNGVIIAADNLGSYGSLLRFNGVE
RLIPVGDNTVVGISGDISDMQHIERLLKDLVTENAYDNPL
ADAEEALEPSYIFEYLATVMYQRRSKMNPLWNAIIVAGVQ
SNGDQFLRYVNLLGVTYSSPTLATGFGAHMANPLLRKVVD
RESDIPKTTVQVAEEAIVNAMRVLYYRDARSSRNFSLAII
DKNTGLTFKKNLQVENMKWDFAKDIKGYGTQKI
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Description
|
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Functional site
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1)
|
chain |
a |
| residue |
34 |
| type |
|
| sequence |
L
|
| description |
binding site for residue MG N 202
|
| source |
: AD1
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|
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2)
|
chain |
a |
| residue |
12-59 |
| type |
prosite |
| sequence |
ISMKYDNGVIIAADNLGSYGSLLRFNGVERLIPVGDNTVV
GISGDISD
|
| description |
PROTEASOME_BETA_1 Proteasome beta-type subunits signature. ISMkYdnGVIIAADnlgsygsllrfngve.RlipvgdntvvgisGdiSD
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| source |
prosite : PS00854
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