eF-site ID 6hwd-Y PDB Code 6hwd Chain Y click to enlarge Title Yeast 20S proteasome beta2-G45A mutant in complex with bortezomib Classification HYDROLASE Compound Proteasome subunit alpha type-2 Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae S288c; Sequence Y:  TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPF LLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAAS KILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRS ILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKV KEEEGSFNNVIG Description Functional site 1) chain Y residue 165 type sequence A description binding site for residue MG I 302 source : AC5 2) chain Y residue 166 type sequence H description binding site for residue MG I 302 source : AC5 3) chain Y residue 168 type sequence D description binding site for residue MG I 302 source : AC5 4) chain Y residue 169 type sequence A description binding site for residue MG I 302 source : AC5 5) chain Y residue 171 type sequence S description binding site for residue MG I 302 source : AC5 6) chain Y residue 2 type sequence T description binding site for Di-peptide BO2 Y 301 and THR Y 1 source : AD6 7) chain Y residue 3 type sequence T description binding site for Di-peptide BO2 Y 301 and THR Y 1 source : AD6 8) chain Y residue 17 type sequence D description binding site for Di-peptide BO2 Y 301 and THR Y 1 source : AD6 9) chain Y residue 20 type sequence A description binding site for Di-peptide BO2 Y 301 and THR Y 1 source : AD6 10) chain Y residue 21 type sequence T description binding site for Di-peptide BO2 Y 301 and THR Y 1 source : AD6 11) chain Y residue 27 type sequence A description binding site for Di-peptide BO2 Y 301 and THR Y 1 source : AD6 12) chain Y residue 33 type sequence K description binding site for Di-peptide BO2 Y 301 and THR Y 1 source : AD6 13) chain Y residue 45 type sequence M description binding site for Di-peptide BO2 Y 301 and THR Y 1 source : AD6 14) chain Y residue 46 type sequence A description binding site for Di-peptide BO2 Y 301 and THR Y 1 source : AD6 15) chain Y residue 47 type sequence G description binding site for Di-peptide BO2 Y 301 and THR Y 1 source : AD6 16) chain Y residue 49 type sequence A description binding site for Di-peptide BO2 Y 301 and THR Y 1 source : AD6 17) chain Y residue 130 type sequence G description binding site for Di-peptide BO2 Y 301 and THR Y 1 source : AD6 18) chain Y residue 131 type sequence S description binding site for Di-peptide BO2 Y 301 and THR Y 1 source : AD6 19) chain Y residue 132 type sequence G description binding site for Di-peptide BO2 Y 301 and THR Y 1 source : AD6 20) chain Y residue 170 type sequence Y description binding site for Di-peptide BO2 Y 301 and THR Y 1 source : AD6 21) chain Y residue 171 type sequence S description binding site for Di-peptide BO2 Y 301 and THR Y 1 source : AD6 22) chain Y residue 49 type BINDING sequence A description source Swiss-Prot : SWS_FT_FI2

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