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eF-site ID
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6hvs-B |
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PDB Code
|
6hvs |
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Chain
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B |
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click to enlarge
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Title
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Yeast 20S proteasome with human beta2i (1-53) in complex with 18 |
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Classification
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HYDROLASE |
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Compound
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Proteasome subunit alpha type-2 |
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Source
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ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae S288C; |
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Sequence
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B: |
GSRRYDSRTTIFSPEGRLYQVEYALESISHAGTAIGIMAS
DGIVLAAERKVTSTLLEQDTSTEKLYKLNDKIAVAVAGLT
ADAEILINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQG
YTQHGGLRPFGVSFIYAGYDDRYGYQLYTSNPSGNYTGWK
AISVGANTSAAQTLLQMDYKDDMKVDDAIELALKTLSKTT
DSSALTYDRLEFATIRKGANDGEVYQKIFKPQEIKDILVK
TGIT
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Description
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Functional site
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1)
|
chain |
B |
| residue |
5-27 |
| type |
prosite |
| sequence |
YDSRTTIFSPEGRLYQVEYALES
|
| description |
PROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. YdralSiFSPdGHifQVEYAleA
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| source |
prosite : PS00388
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|
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2)
|
chain |
B |
| residue |
35-82 |
| type |
prosite |
| sequence |
IGIMASDGIVLAAERKVTSTLLEQDTSTEKLYKLNDKIAV
AVAGLTAD
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| description |
PROTEASOME_BETA_1 Proteasome beta-type subunits signature. MAVtFkdGVILGADsrtttgayianrvtd.KltrvhdkiwccrsGsaAD
|
| source |
prosite : PS00854
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3)
|
chain |
B |
| residue |
198 |
| type |
ACT_SITE |
| sequence |
K
|
| description |
Nucleophile => ECO:0000269|PubMed:9087403
|
| source |
Swiss-Prot : SWS_FT_FI1
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|
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4)
|
chain |
B |
| residue |
230 |
| type |
ACT_SITE |
| sequence |
K
|
| description |
Nucleophile => ECO:0000269|PubMed:9087403
|
| source |
Swiss-Prot : SWS_FT_FI1
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