eF-site ID 6hub-I
PDB Code 6hub
Chain I

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Title Yeast 20S proteasome with human beta2c (S171G) in complex with 16
Classification HYDROLASE
Compound Proteasome subunit alpha type-2
Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae (strain ATCC 204508 / S288c);
Sequence I:  SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFE
KIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERA
IEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFI
AGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPE
DLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLK
MRQD
Description


Functional site

1) chain I
residue 124
type
sequence D
description binding site for residue GRW H 301
source : AC3

2) chain I
residue 125
type
sequence L
description binding site for residue GRW H 301
source : AC3

3) chain I
residue 174
type
sequence A
description binding site for residue MG I 301
source : AC4

4) chain I
residue 177
type
sequence D
description binding site for residue MG I 301
source : AC4

5) chain I
residue 180
type
sequence S
description binding site for residue MG I 301
source : AC4

6) chain I
residue 204
type
sequence D
description binding site for residue MG I 301
source : AC4

7) chain I
residue 204
type
sequence D
description binding site for residue MG I 302
source : AC5

8) chain I
residue 12-58
type prosite
sequence VAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYGHVFLG
ITGLATD
description PROTEASOME_BETA_1 Proteasome beta-type subunits signature. MAVtFkdGVILGADsrtttgayianrvtd.KltrvhdkiwccrsGsaAD
source prosite : PS00854


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