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eF-site ID
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6hrb-A |
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PDB Code
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6hrb |
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Chain
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A |
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click to enlarge
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Title
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Cryo-EM structure of the KdpFABC complex in an E2 inward-facing state (state 2) |
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Classification
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MEMBRANE PROTEIN |
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Compound
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Potassium-transporting ATPase potassium-binding subunit |
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Source
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(KDPF_ECOLI) |
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Sequence
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A: |
MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTT
GVERVLFRALGVSDREMNWKQYLCAILGLNMLGLAVLFFM
LLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSG
ETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSM
STLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFLP
YQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANS
SHPFENPTALTNFVQMLAIFLIPTALCFAFGEVMGDRRQG
RMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGTDSSINM
EGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGM
VPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGR
TPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDA
GRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPF
WNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQAASSGTL
PTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS
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Description
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(1) |
Potassium-transporting ATPase potassium-binding subunit, Potassium-transporting ATPase ATP-binding subunit (E.C.3.6.3.12), Potassium-transporting ATPase KdpC subunit, Potassium-transporting ATPase KdpF subunit
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Functional site
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|
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1)
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chain |
A |
| residue |
378 |
| type |
|
| sequence |
S
|
| description |
binding site for residue K A 601
|
| source |
: AC1
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2)
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chain |
A |
| residue |
436-479 |
| type |
TOPO_DOM |
| sequence |
MMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLS
ANSP
|
| description |
Periplasmic => ECO:0000269|PubMed:28636601, ECO:0000269|PubMed:30478378
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| source |
Swiss-Prot : SWS_FT_FI1
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3)
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chain |
A |
| residue |
553-557 |
| type |
TOPO_DOM |
| sequence |
AEYLS
|
| description |
Periplasmic => ECO:0000269|PubMed:28636601, ECO:0000269|PubMed:30478378
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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4)
|
chain |
A |
| residue |
525-552 |
| type |
TRANSMEM |
| sequence |
PLFVGLLIGTVLLVGALTFIPALALGPV
|
| description |
Helical => ECO:0000269|PubMed:28636601, ECO:0000269|PubMed:30478378, ECO:0007744|PDB:5MRW, ECO:0007744|PDB:6HRA
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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5)
|
chain |
A |
| residue |
415-435 |
| type |
TRANSMEM |
| sequence |
KLTALAILVTPTLVLMGAALA
|
| description |
Helical => ECO:0000269|PubMed:28636601, ECO:0000269|PubMed:30478378, ECO:0007744|PDB:5MRW, ECO:0007744|PDB:6HRA
|
| source |
Swiss-Prot : SWS_FT_FI2
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|
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6)
|
chain |
A |
| residue |
480-501 |
| type |
TRANSMEM |
| sequence |
FWNCLLAFCMFVGRFGVIIPVM
|
| description |
Helical => ECO:0000269|PubMed:28636601, ECO:0000269|PubMed:30478378, ECO:0007744|PDB:5MRW, ECO:0007744|PDB:6HRA
|
| source |
Swiss-Prot : SWS_FT_FI2
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7)
|
chain |
A |
| residue |
502-524 |
| type |
TOPO_DOM |
| sequence |
AIAGSLVSKKSQAASSGTLPTHG
|
| description |
Cytoplasmic => ECO:0000269|PubMed:28636601, ECO:0000269|PubMed:30478378
|
| source |
Swiss-Prot : SWS_FT_FI3
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