eF-site ID 6hpr-ABCD PDB Code 6hpr Chain A, B, C, D click to enlarge Title Crystal structure of cIAP1 RING domain bound to UbcH5B-Ub and a non-covalent Ub Classification LIGASE Compound Baculoviral IAP repeat-containing protein 2 Source (UB2D2_HUMAN) Sequence A:  LSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQEC APSLRKCPICRGIIKGTVRTFLS B:  GGSMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIP PDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLR C:  ALKRIHKELNDLARDPPAQCSAGPVGDDMFHWQATIMGPN DSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSN GSIKLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVP EIARIYKTDREKYNRIAREWTQKYAM D:  GSMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPP DQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG Description Functional site 1) chain A residue 571 type sequence C description binding site for residue ZN A 701 source : AC1 2) chain A residue 574 type sequence C description binding site for residue ZN A 701 source : AC1 3) chain A residue 592 type sequence C description binding site for residue ZN A 701 source : AC1 4) chain A residue 595 type sequence C description binding site for residue ZN A 701 source : AC1 5) chain A residue 586 type sequence C description binding site for residue ZN A 702 source : AC2 6) chain A residue 588 type sequence H description binding site for residue ZN A 702 source : AC2 7) chain A residue 602 type sequence C description binding site for residue ZN A 702 source : AC2 8) chain A residue 605 type sequence C description binding site for residue ZN A 702 source : AC2 9) chain B residue -1 type CROSSLNK sequence G description Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins) source Swiss-Prot : SWS_FT_FI2 10) chain D residue -1 type CROSSLNK sequence G description Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins) source Swiss-Prot : SWS_FT_FI2 11) chain B residue 27-52 type prosite sequence KAKIQDKEGIPPDQQRLIFAGKQLED description UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD source prosite : PS00299 12) chain C residue 85 type ACT_SITE sequence K description Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388, ECO:0000255|PROSITE-ProRule:PRU10133 source Swiss-Prot : SWS_FT_FI1 13) chain D residue -1 type ACT_SITE sequence G description Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388, ECO:0000255|PROSITE-ProRule:PRU10133 source Swiss-Prot : SWS_FT_FI1

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