eF-site ID 6hfb-ABCD PDB Code 6hfb Chain A, B, C, D click to enlarge Title Outward-facing conformation of a multidrug resistance MATE family transporter of the MOP superfamily. Classification MEMBRANE PROTEIN Compound Uncharacterized protein Source (Q8U2X0_PYRFU) Sequence A:  KTTKGVQLLRGDPKKAIVRLSIPMMIGMSVQTLYNLADGI WVSGLGPESLAAVGLFFPVFMGIIALAAGLGVGTSSAIAR RIGARDKEGADNVAVHSLILSLILGVTITITMLPAIDSLF RSMGAKGEAVELAIEYARVLLAGAFIIVFNNVGNGILRGE GDANRAMLAMVLGSGLNIVLDPIFIYTLGFGVVGAAYATL LSMVVTSLFIAYWLFVKRDTYVDITLRDFSPSREILKDIL RVGLPSSLSQLSMSIAMFFLNSVAITAGGENGVAVFTSAW RITMLGIVPILGMATATTSVTGAAYGERNVEKLETAYLYA IKIAFMIELAVVAFIMLFAPQVAYLFTYSESAQVIKGDLI SALRTLPVFLVLTPFGMMTSAMFQGIGEGEKSLILTIFRT LVMQVGFAYIFVHYTTLGLRGVWIGIVIGNMVAAIVGFLW GRMRISALKKTSA B:  EKTTKGVQLLRGDPKKAIVRLSIPMMIGMSVQTLYNLADG IWVSGLGPESLAAVGLFFPVFMGIIALAAGLGVGTSSAIA RRIGARDKEGADNVAVHSLILSLILGVTITITMLPAIDSL FRSMGAKGEAVELAIEYARVLLAGAFIIVFNNVGNGILRG EGDANRAMLAMVLGSGLNIVLDPIFIYTLGFGVVGAAYAT LLSMVVTSLFIAYWLFVKRDTYVDITLRDFSPSREILKDI LRVGLPSSLSQLSMSIAMFFLNSVAITAGGENGVAVFTSA WRITMLGIVPILGMATATTSVTGAAYGERNVEKLETAYLY AIKIAFMIELAVVAFIMLFAPQVAYLFTYSSAQVIKGDLI SALRTLPVFLVLTPFGMMTSAMFQGIGEGEKSLILTIFRT LVMQVGFAYIFVHYTTLGLRGVWIGIVIGNMVAAIVGFLW GRMRISALKKTSA C:  EKTTKGVQLLRGDPKKAIVRLSIPMMIGMSVQTLYNLADG IWVSGLGPESLAAVGLFFPVFMGIIALAAGLGVGTSSAIA RRIGARDKEGADNVAVHSLILSLILGVTITITMLPAIDSL FRSMGAKGEAVELAIEYARVLLAGAFIIVFNNVGNGILRG EGDANRAMLAMVLGSGLNIVLDPIFIYTLGFGVVGAAYAT LLSMVVTSLFIAYWLFVKRDTYVDITLRDFSPSREILKDI LRVGLPSSLSQLSMSIAMFFLNSVAITAGGENGVAVFTSA WRITMLGIVPILGMATATTSVTGAAYGERNVEKLETAYLY AIKIAFMIELAVVAFIMLFAPQVAYLFTYSSAQVIKGDLI SALRTLPVFLVLTPFGMMTSAMFQGIGEGEKSLILTIFRT LVMQVGFAYIFVHYTTLGLRGVWIGIVIGNMVAAIVGFLW GRMRISALKKT D:  EKTTKGVQLLRGDPKKAIVRLSIPMMIGMSVQTLYNLADG IWVSGLGPESLAAVGLFFPVFMGIIALAAGLGVGTSSAIA RRIGARDKEGADNVAVHSLILSLILGVTITITMLPAIDSL FRSMGAKGEAVELAIEYARVLLAGAFIIVFNNVGNGILRG EGDANRAMLAMVLGSGLNIVLDPIFIYTLGFGVVGAAYAT LLSMVVTSLFIAYWLFVKRDTYVDITLRDFSPSREILKDI LRVGLPSSLSQLSMSIAMFFLNSVAITAGGENGVAVFTSA WRITMLGIVPILGMATATTSVTGAAYGERNVEKLETAYLY AIKIAFMIELAVVAFIMLFAPQVAYLFTYSESAVIKGDLI SALRTLPVFLVLTPFGMMTSAMFQGIGEGEKSLILTIFRT LVMQVGFAYIFVHYTTLGLRGVWIGIVIGNMVAAIVGFLW GRMRISALKKT Description Functional site 1) chain A residue 221 type sequence R description binding site for residue CS A 501 source : AC1 2) chain A residue 223 type sequence T description binding site for residue CS A 501 source : AC1 3) chain A residue 225 type sequence V description binding site for residue CS A 501 source : AC1 4) chain A residue 226 type sequence D description binding site for residue CS A 501 source : AC1 5) chain A residue 41 type sequence D description binding site for residue CS A 502 source : AC2 6) chain A residue 145 type sequence A description binding site for residue CS A 504 source : AC3 7) chain B residue 221 type sequence R description binding site for residue CS B 501 source : AC4 8) chain B residue 223 type sequence T description binding site for residue CS B 501 source : AC4 9) chain B residue 225 type sequence V description binding site for residue CS B 501 source : AC4 10) chain B residue 226 type sequence D description binding site for residue CS B 501 source : AC4 11) chain B residue 416 type sequence H description binding site for residue CS B 502 source : AC5 12) chain B residue 416 type sequence H description binding site for residue CS B 502 source : AC5 13) chain C residue 221 type sequence R description binding site for residue CS C 501 source : AC6 14) chain C residue 223 type sequence T description binding site for residue CS C 501 source : AC6 15) chain C residue 225 type sequence V description binding site for residue CS C 501 source : AC6 16) chain C residue 226 type sequence D description binding site for residue CS C 501 source : AC6 17) chain C residue 41 type sequence D description binding site for residue CS C 502 source : AC7 18) chain C residue 415 type sequence V description binding site for residue CS C 503 source : AC8 19) chain D residue 221 type sequence R description binding site for residue CS D 501 source : AC9 20) chain D residue 223 type sequence T description binding site for residue CS D 501 source : AC9 21) chain D residue 225 type sequence V description binding site for residue CS D 501 source : AC9 22) chain D residue 226 type sequence D description binding site for residue CS D 501 source : AC9 23) chain B residue 419 type sequence T description binding site for residue CS D 503 source : AD1 24) chain D residue 415 type sequence V description binding site for residue CS D 503 source : AD1 25) chain D residue 418 type sequence T description binding site for residue CS D 503 source : AD1

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