eF-site ID 6h7s-A PDB Code 6h7s Chain A click to enlarge Title Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase T157V/A198L variant in complex with L-2-keto-3deoxy-gluconate Classification LYASE Compound 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase Source (KDGA_SULSF) Sequence A:  PEIITPIITPFTKDNRIDKEKLKIHAENLIRKGIDKLFVN GTTGLGPSLSPEEKLENLKAVYDVTNKIIFQVGGLNLDDA IRLAKLSKDFDIVGIASYAPYYYPRMSEKHLVKYFKTLCE VSPHPVYLYNYPTATGKDIDAKVAKEIGCFTGVKDVIENI IHTLDYKRLNPNMLVYSGSDMLIATVASTGLDGNVALGSN YLPEVTVTIKKLAMERKIDEALKLQFLHDEVIEASRIFGS LSSNYVLTKYFQGYDLGYPRPPIFPLDDEEERQLIKKVEG IRAKLVELKILKE Description Functional site 1) chain A residue 7 type sequence P description binding site for residue FW2 A 301 source : AC1 2) chain A residue 39 type sequence F description binding site for residue FW2 A 301 source : AC1 3) chain A residue 42 type sequence G description binding site for residue FW2 A 301 source : AC1 4) chain A residue 43 type sequence T description binding site for residue FW2 A 301 source : AC1 5) chain A residue 44 type sequence T description binding site for residue FW2 A 301 source : AC1 6) chain A residue 130 type sequence Y description binding site for residue FW2 A 301 source : AC1 7) chain A residue 132 type sequence Y description binding site for residue FW2 A 301 source : AC1 8) chain A residue 155 type sequence K description binding site for residue FW2 A 301 source : AC1 9) chain A residue 179 type sequence G description binding site for residue FW2 A 301 source : AC1 10) chain A residue 196 type sequence V description binding site for residue FW2 A 301 source : AC1 11) chain A residue 155 type ACT_SITE sequence K description Schiff-base intermediate with substrate => ECO:0000269|PubMed:15265860 source Swiss-Prot : SWS_FT_FI1 12) chain A residue 43 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI2 13) chain A residue 130 type BINDING sequence Y description source Swiss-Prot : SWS_FT_FI2 14) chain A residue 155 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI2 15) chain A residue 130 type SITE sequence Y description Proton shuttle => ECO:0000250 source Swiss-Prot : SWS_FT_FI3

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