eF-site ID 6h4g-B PDB Code 6h4g Chain B click to enlarge Title Regulatory subunit of a cAMP-independent protein kinase A from Trypanosoma brucei: E311A, T318R, V319A mutant bound to cAMP in the A site Classification SIGNALING PROTEIN Compound Protein kinase A regulatory subunit Source (Q385V6_TRYB2) Sequence B:  YVAPYFEKSEDETALILKLLTYNVLFSFLDSRDLMTVAGA MWRVEFKQDDCIMEAGQTTCDKLYIIQDGKADIIKEGQKV YLKVEGTAVGELALMYQTPRAATVKVCTPELIAWALDRDT YRHLVMGSAIRRRETYIQFLTNIPFLSGLDNYEKLQLADA LSSDEFEPGDYIIRYGEEGEWLYIILEGSVDVVGRDDDGN EKHVWEFGKGDHVGELEFLNNHANVADVVAKTHVVTAKLN RRHFEMCLGPVIDVLKRTSQQPNYEYYQSKLK Description Functional site 1) chain B residue 271 type sequence M description binding site for residue CMP B 501 source : AC3 2) chain B residue 291 type sequence I description binding site for residue CMP B 501 source : AC3 3) chain B residue 299 type sequence Y description binding site for residue CMP B 501 source : AC3 4) chain B residue 307 type sequence V description binding site for residue CMP B 501 source : AC3 5) chain B residue 308 type sequence G description binding site for residue CMP B 501 source : AC3 6) chain B residue 309 type sequence E description binding site for residue CMP B 501 source : AC3 7) chain B residue 310 type sequence L description binding site for residue CMP B 501 source : AC3 8) chain B residue 311 type sequence A description binding site for residue CMP B 501 source : AC3 9) chain B residue 318 type sequence R description binding site for residue CMP B 501 source : AC3 10) chain B residue 319 type sequence A description binding site for residue CMP B 501 source : AC3 11) chain B residue 320 type sequence A description binding site for residue CMP B 501 source : AC3 12) chain B residue 370 type sequence Y description binding site for residue CMP B 501 source : AC3 13) chain B residue 410 type sequence V description binding site for residue NOS B 502 source : AC4 14) chain B residue 422 type sequence V description binding site for residue NOS B 502 source : AC4 15) chain B residue 425 type sequence F description binding site for residue NOS B 502 source : AC4 16) chain B residue 431 type sequence V description binding site for residue NOS B 502 source : AC4 17) chain B residue 432 type sequence G description binding site for residue NOS B 502 source : AC4 18) chain B residue 433 type sequence E description binding site for residue NOS B 502 source : AC4 19) chain B residue 434 type sequence L description binding site for residue NOS B 502 source : AC4 20) chain B residue 435 type sequence E description binding site for residue NOS B 502 source : AC4 21) chain B residue 443 type sequence V description binding site for residue NOS B 502 source : AC4 22) chain B residue 444 type sequence A description binding site for residue NOS B 502 source : AC4 23) chain B residue 481 type sequence N description binding site for residue NOS B 502 source : AC4 24) chain B residue 482 type sequence Y description binding site for residue NOS B 502 source : AC4 25) chain B residue 484 type sequence Y description binding site for residue NOS B 502 source : AC4 26) chain B residue 485 type sequence Y description binding site for residue NOS B 502 source : AC4

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